Thermo Scientific™

Hypersil GOLD™ PREP aQ HPLC Columns

Catalog number: 25305-018823A
Thermo Scientific™

Hypersil GOLD™ PREP aQ HPLC Columns

Catalog number: 25305-018823A

Retain and resolve polar analytes for your scale up purification needs by using Thermo Scientific™ Hypersil GOLD™ aQ Polar Endcapped C18 preparative columns. These C18 preparative HPLC columns are perfect for challenging reversed phase separations using highly aqueous mobile phases. Our columns come in a wide range of dimensions and an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed.

 
Catalog Number
25305-018823A
Unit Size
Each
Column Format
Guard Column
Diameter (Metric)
10 mm
Length (Metric)
8 mm
Particle Size
5 μm
Price (USD)
Full specifications
Column FormatGuard Column
Diameter (Metric)10 mm
For Use WithGuard Column Requires Use of Preparative Guard Holder, 885-010
Length (Metric)8 mm
Max. Pressure4300 psi (295 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Column Format
Guard Column
Diameter (Metric)
10 mm
Length (Metric)
20 mm
Particle Size
5 μm
Price (USD)
Full specifications
Column FormatGuard Column
Diameter (Metric)10 mm
For Use WithGuard Column Requires Use of Preparative Guard Holder, 887-020
Length (Metric)20 mm
Max. Pressure4300 psi (295 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Column Format
Guard Column, 1/16 in.
Diameter (Metric)
10 mm
Length (Metric)
30 mm
Particle Size
5 μm
Price (USD)
Full specifications
Column FormatGuard Column, 1/16 in.
Diameter (Metric)10 mm
For Use WithGuard Column Requires Use of Preparative Guard Holder, 887-030
Length (Metric)30 mm
Max. Pressure2200 psi (152 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Column Format
Guard Column, 1/8 in.
Diameter (Metric)
10 mm
Length (Metric)
30 mm
Particle Size
5 μm
Price (USD)
Full specifications
Column FormatGuard Column, 1/8 in.
Diameter (Metric)10 mm
For Use WithGuard Column Requires Use of Preparative Guard Holder, 887-031
Length (Metric)30 mm
Max. Pressure2200 psi (152 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Column Format
Guard Column
Diameter (Metric)
20 mm
Length (Metric)
20 mm
Particle Size
5 μm
Price (USD)
Full specifications
Column FormatGuard Column
Diameter (Metric)20 mm
For Use WithGuard Column Requires Use of Preparative Guard Holder, 889-020
Length (Metric)20 mm
Max. Pressure4300 psi (295 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Column Format
Guard Column, 1/16 in.
Diameter (Metric)
20 mm
Length (Metric)
30 mm
Particle Size
5 μm
Price (USD)
Full specifications
Column FormatGuard Column, 1/16 in.
Diameter (Metric)20 mm
For Use WithGuard Column Requires Use of Preparative Guard Holder, 891-030
Length (Metric)30 mm
Max. Pressure2200 psi (152 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Column Format
Guard Column, 1/8 in.
Diameter (Metric)
20 mm
Length (Metric)
30 mm
Particle Size
5 μm
Price (USD)
Full specifications
Column FormatGuard Column, 1/8 in.
Diameter (Metric)20 mm
For Use WithGuard Column Requires Use of Preparative Guard Holder, 891-031
Length (Metric)30 mm
Max. Pressure2200 psi (152 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Column Format
Preparative Column, Standard
Diameter (Metric)
10 mm
Length (Metric)
100 mm
Particle Size
5 μm
Price (USD)
Full specifications
Column FormatPreparative Column, Standard
Diameter (Metric)10 mm
Length (Metric)100 mm
Max. Pressure4300 psi (295 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Column Format
Preparative Column, Standard
Diameter (Metric)
10 mm
Length (Metric)
100 mm
Particle Size
5 μm
Price (USD)
Full specifications
Column FormatPreparative Column, Standard
Diameter (Metric)10 mm
Length (Metric)100 mm
Max. Pressure4300 psi (295 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Column Format
Preparative Column, XtendedLife
Diameter (Metric)
25 mm
Length (Metric)
100 mm
Particle Size
5 μm
Price (USD)
Full specifications
Column FormatPreparative Column, XtendedLife
Diameter (Metric)25 mm
Length (Metric)100 mm
Max. Pressure3500 psi (240 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
Showing 10 of 28Show more
Catalog NumberSpecificationsUnit SizeColumn FormatDiameter (Metric)Length (Metric)Particle SizePrice (USD)
25305-018823AFull specifications
EachGuard Column10 mm8 mm5 μmContact Us ›
Column FormatGuard Column
Diameter (Metric)10 mm
For Use WithGuard Column Requires Use of Preparative Guard Holder, 885-010
Length (Metric)8 mm
Max. Pressure4300 psi (295 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
25305-019023AFull specifications
EachGuard Column10 mm20 mm5 μmContact Us ›
Column FormatGuard Column
Diameter (Metric)10 mm
For Use WithGuard Column Requires Use of Preparative Guard Holder, 887-020
Length (Metric)20 mm
Max. Pressure4300 psi (295 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
25305-019323AFull specifications
EachGuard Column, 1/16 in.10 mm30 mm5 μmContact Us ›
Column FormatGuard Column, 1/16 in.
Diameter (Metric)10 mm
For Use WithGuard Column Requires Use of Preparative Guard Holder, 887-030
Length (Metric)30 mm
Max. Pressure2200 psi (152 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
25305-019323BFull specifications
EachGuard Column, 1/8 in.10 mm30 mm5 μmContact Us ›
Column FormatGuard Column, 1/8 in.
Diameter (Metric)10 mm
For Use WithGuard Column Requires Use of Preparative Guard Holder, 887-031
Length (Metric)30 mm
Max. Pressure2200 psi (152 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
25305-029023AFull specifications
EachGuard Column20 mm20 mm5 μmContact Us ›
Column FormatGuard Column
Diameter (Metric)20 mm
For Use WithGuard Column Requires Use of Preparative Guard Holder, 889-020
Length (Metric)20 mm
Max. Pressure4300 psi (295 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
25305-029323AFull specifications
EachGuard Column, 1/16 in.20 mm30 mm5 μmContact Us ›
Column FormatGuard Column, 1/16 in.
Diameter (Metric)20 mm
For Use WithGuard Column Requires Use of Preparative Guard Holder, 891-030
Length (Metric)30 mm
Max. Pressure2200 psi (152 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
25305-029323BFull specifications
EachGuard Column, 1/8 in.20 mm30 mm5 μmContact Us ›
Column FormatGuard Column, 1/8 in.
Diameter (Metric)20 mm
For Use WithGuard Column Requires Use of Preparative Guard Holder, 891-031
Length (Metric)30 mm
Max. Pressure2200 psi (152 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
25305-109070AFull specifications
EachPreparative Column, Standard10 mm100 mm5 μmContact Us ›
Column FormatPreparative Column, Standard
Diameter (Metric)10 mm
Length (Metric)100 mm
Max. Pressure4300 psi (295 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
25305-109270AFull specifications
EachPreparative Column, Standard10 mm100 mm5 μmContact Us ›
Column FormatPreparative Column, Standard
Diameter (Metric)10 mm
Length (Metric)100 mm
Max. Pressure4300 psi (295 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
25305-109270XLFull specifications
EachPreparative Column, XtendedLife25 mm100 mm5 μmContact Us ›
Column FormatPreparative Column, XtendedLife
Diameter (Metric)25 mm
Length (Metric)100 mm
Max. Pressure3500 psi (240 bar)
Particle Size5 μm
pH2 to 9
Pore Size175 Å
Surface Area220 m²/g
Temperature60°C
USP TypeL1
Stationary PhaseaQ C18
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load12%
Column TypeReversed Phase
EndcappedPolar
PhaseReversed Phase
Unit SizeEach
Showing 10 of 28Show more

Alternative selectivity with polar endcapped C18 stationary phase

  • Polar functional group in endcap provides further interaction mechanism for separation of polar compounds.
  • Yields superior retention of polar compounds.
  • C18 (USP L1) selectivity.

Stability in highly aqueous mobile phases

  • Applicable in 100% aqueous mobile phases.
  • No loss of performance or stability.

Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs.

Standard Threaded and Standard Flange Hardware

  • Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use.
  • Standard threaded hardware for column i.d. < 40mm.
  • Standard flange hardware for column i.d. ≥ 40mm.
  • Standard hardware can be modified on request to be compatible with SFC.

XtendedLife Hardware

  • Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly.
  • Compatible with SFC and is available in dimensions up to 50mm i.d.

Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.

Customer Specific Orders

  • If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in a preparative scale not shown or would like to discuss a specific column dimension, we would be happy to discuss your requirements.
  • Please contact your local sales representative for Customer Specific Orders.
  • Custom built columns are not eligible for returns.

About the Hypersil GOLD family of HPLC columns

Meet the challenges of modern chromatography with state-of-the-art columns that provide outstanding performance and consistent separations. Twelve different chemistries are available so you can optimize separations and maximize productivity. Get outstanding peak shapes in reversed phase, ion exchange, HILIC, or normal phase chromatography.