Thermo Scientific™

2'-Fluoro-Bz-A Phosphoramidite, standard grade, 20-400 finish bottle

Catalog number: 27-1601-09
Thermo Scientific™

2'-Fluoro-Bz-A Phosphoramidite, standard grade, 20-400 finish bottle

Catalog number: 27-1601-09
Catalog Number
27-1601-09
Unit Size
0.25 g
Price (USD)
Price: 45.55
Your Price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
27-1601-090.25 g
Price: 45.55
Your Price:
-
Product Overview
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2'-Fluoro-Bz-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.

Features:
• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-fluoroadenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C47H51FN7O7P
• Base—A
• Base Protection—Bz
• Formula weight—875.92 g/mol
• CAS number—NA!!
• HPLC purity—>98%
31P NMR purity—≥98%

Specifications

Form
Powder
HPLC Purity
0.98
For Use With (Equipment)
Expedite Synthesizers
Chemical Name or Material
2in-Fluoro-Bz-A CEP
Nucleoside Type
Adenosine (A)
Reagent Features
2in-Fluoro modified
Shipping Condition
Room Temperature
Reagent Type
Phosphoramidite
Purity or Quality Grade
Standard
Nucleic Acid Type
RNA

Contents & Storage

Store in freezer (at or below -20°C).