Thermo Scientific™

2'-Fluoro-iBu-G Phosphoramidite, standard grade, serum vial bottle

Catalog number: 27-1607-02
Thermo Scientific™

2'-Fluoro-iBu-G Phosphoramidite, standard grade, serum vial bottle

Catalog number: 27-1607-02
Catalog Number
27-1607-02
Unit Size
1 g
Price (USD)
Price: 151.00
Your Price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
27-1607-021 g
Price: 151.00
Your Price:
-
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2'-Fluoro-iBu-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 20-mL amber bottle with a serum vial neck style, which is compatible with most Applied Biosystems synthesizers and AKTA synthesizers.

Features:
• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-fluoroguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C44H53FN7O8P
• Base—G
• Base Protection—iBu
• Formula weight—857.4 g/mol
• CAS number—144089-97-4
• HPLC purity—>98%
31P NMR purity—≥98%

Specifications

Form
Powder
HPLC Purity
0.98
For Use With (Equipment)
AKTA Synthesizers, Applied Biosystems Synthesizers
Chemical Name or Material
2in-Fluoro-iBu-G CEP
Nucleoside Type
Guanosine (G)
Reagent Features
2in-Fluoro modified
Shipping Condition
Room Temperature
Reagent Type
Phosphoramidite
Purity or Quality Grade
Standard
Nucleic Acid Type
RNA

Contents & Storage

Store in freezer (at or below -20°C).