Thermo Scientific™

Hypersil™ PREP HS C8 HPLC Columns

Catalog number: 41103-052130
Thermo Scientific™

Hypersil™ PREP HS C8 HPLC Columns

Catalog number: 41103-052130

Get maximum loading for your scale up from analytical to a prep LC method with Thermo Scientific™ Hypersil™ PREP HS C8 reversed phase preparative HPLC column. With similar selectivity to C18 columns and predictable elution order, C8 columns are ideal for analytes with medium hydrophobicity or when a less hydrophobic phase is required to obtain optimum retention. The lower hydrophobicity allows compounds to elute more quickly, yielding faster separations. By providing high surface area particles with a 100Å pore size, and a variety of dimensions including an option for XtendedLife hardware, which improves column lifetime by maintaining a uniform packed bed.

 
Catalog Number
41103-052130
Unit Size
Each
Particle Size
3 μm
Diameter (Metric)
2 mm
Length (Metric)
50 mm
Price (USD)
Full specifications
Column FormatPreparative Column, Standard
Diameter (Metric)2 mm
Length (Metric)50 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Particle Size
3 μm
Diameter (Metric)
4.6 mm
Length (Metric)
50 mm
Price (USD)
Full specifications
Column FormatPreparative Column, Standard
Diameter (Metric)4.6 mm
Length (Metric)50 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Particle Size
3 μm
Diameter (Metric)
2 mm
Length (Metric)
100 mm
Price (USD)
Full specifications
Column FormatPreparative Column, Standard
Diameter (Metric)2 mm
Length (Metric)100 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Particle Size
3 μm
Diameter (Metric)
4.6 mm
Length (Metric)
100 mm
Price (USD)
Full specifications
Column FormatPreparative Column, Standard
Diameter (Metric)4.6 mm
Length (Metric)100 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Particle Size
3 μm
Diameter (Metric)
2 mm
Length (Metric)
150 mm
Price (USD)
Full specifications
Column FormatPreparative Column, Standard
Diameter (Metric)2 mm
Length (Metric)150 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Particle Size
3 μm
Diameter (Metric)
4.6 mm
Length (Metric)
150 mm
Price (USD)
Full specifications
Column FormatPreparative Column, Standard
Diameter (Metric)4.6 mm
Length (Metric)150 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Particle Size
3 μm
Diameter (Metric)
2 mm
Length (Metric)
250 mm
Price (USD)
Full specifications
Column FormatPreparative Column, Standard
Diameter (Metric)2 mm
Length (Metric)250 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Particle Size
3 μm
Diameter (Metric)
4.6 mm
Length (Metric)
250 mm
Price (USD)
Full specifications
Column FormatPreparative Column, Standard
Diameter (Metric)4.6 mm
Length (Metric)250 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Particle Size
5 μm
Diameter (Metric)
2 mm
Length (Metric)
50 mm
Price (USD)
Full specifications
Column FormatPreparative Column, Standard
Diameter (Metric)2 mm
Length (Metric)50 mm
Max. Pressure5800 psi (400 bar)
Particle Size5 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
Catalog Number
Unit Size
Each
Particle Size
5 μm
Diameter (Metric)
4.6 mm
Length (Metric)
50 mm
Price (USD)
Full specifications
Column FormatPreparative Column, Standard
Diameter (Metric)4.6 mm
Length (Metric)50 mm
Max. Pressure5800 psi (400 bar)
Particle Size5 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
Showing 10 of 63Show more
Catalog NumberSpecificationsUnit SizeParticle SizeDiameter (Metric)Length (Metric)Price (USD)
41103-052130Full specifications
Each3 μm2 mm50 mmContact Us ›
Column FormatPreparative Column, Standard
Diameter (Metric)2 mm
Length (Metric)50 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
41103-054630Full specifications
Each3 μm4.6 mm50 mmContact Us ›
Column FormatPreparative Column, Standard
Diameter (Metric)4.6 mm
Length (Metric)50 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
41103-102130Full specifications
Each3 μm2 mm100 mmContact Us ›
Column FormatPreparative Column, Standard
Diameter (Metric)2 mm
Length (Metric)100 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
41103-104630Full specifications
Each3 μm4.6 mm100 mmContact Us ›
Column FormatPreparative Column, Standard
Diameter (Metric)4.6 mm
Length (Metric)100 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
41103-152130Full specifications
Each3 μm2 mm150 mmContact Us ›
Column FormatPreparative Column, Standard
Diameter (Metric)2 mm
Length (Metric)150 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
41103-154630Full specifications
Each3 μm4.6 mm150 mmContact Us ›
Column FormatPreparative Column, Standard
Diameter (Metric)4.6 mm
Length (Metric)150 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
41103-252130Full specifications
Each3 μm2 mm250 mmContact Us ›
Column FormatPreparative Column, Standard
Diameter (Metric)2 mm
Length (Metric)250 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
41103-254630Full specifications
Each3 μm4.6 mm250 mmContact Us ›
Column FormatPreparative Column, Standard
Diameter (Metric)4.6 mm
Length (Metric)250 mm
Max. Pressure5800 psi (400 bar)
Particle Size3 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
41105-052130Full specifications
Each5 μm2 mm50 mmContact Us ›
Column FormatPreparative Column, Standard
Diameter (Metric)2 mm
Length (Metric)50 mm
Max. Pressure5800 psi (400 bar)
Particle Size5 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
41105-054630Full specifications
Each5 μm4.6 mm50 mmContact Us ›
Column FormatPreparative Column, Standard
Diameter (Metric)4.6 mm
Length (Metric)50 mm
Max. Pressure5800 psi (400 bar)
Particle Size5 μm
pH2 to 8
Pore Size100 Å
Surface Area350 m²/g
Temperature60°C
USP TypeL7
Stationary PhaseC8
Packing MaterialSpherical, Fully Porous, Ultrapure Silica
Carbon Load7%
Column TypeReversed Phase
EndcappedYes
PhaseReversed Phase
Unit SizeEach
Showing 10 of 63Show more

Similar selectivity, less retention than C18 columns

  • Successful retention and separation of moderately hydrophobic analytes.
  • Ideal for fatty acids, which are too hydrophobic for analysis using C18 columns.
  • C8 (USP L7) selectivity - high surface area particle with 100Å pore size.
  • pH stable from 2 to 8.
  • Maximum temperature of 60°C.

Faster separations

  • Higher analytical throughput compared to C18 alkyl chain chemistry.
  • Quicker compound elution due to reduced hydrophobic interactions.

Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs.

Standard Threaded and Standard Flange Hardware

  • Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use.
  • Standard threaded hardware for column i.d. < 40mm.
  • Standard flange hardware for column i.d. ≥ 40mm.
  • Standard hardware can be modified on request to be compatible with SFC.

XtendedLife Hardware

  • Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly.
  • Compatible with SFC and is available in dimensions up to 50mm i.d.

Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.

Customer Specific Orders

  • If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in a preparative scale not shown or would like to discuss a specific column dimension, we would be happy to discuss your requirements.
  • Please contact your local sales representative for Customer Specific Orders.
  • Custom built columns are not eligible for returns.