Thermo Scientific™

Pharma 24 Twin-Screw Granulator

Catalog number: 553-4040
Thermo Scientific™

Pharma 24 Twin-Screw Granulator

Catalog number: 553-4040
The Thermo Scientific™ Pharma 24 Twin-Screw Granulator (TSG) is a dedicated system for wet and dry granulation processes. It can be used as a stand-alone instrument or integrated into a modular, continuous manufacturing line that spans from raw materials to final tableting. Such flexibility minimizes scale-up risks.

The Pharma 24 TSG provides consistent and controllable processing, on-demand production, and reduced clean room space and ATEX risk. It is also suitable for process analytical technology (PAT).
 
Catalog Number
553-4040
Unit Size
Each
Description
Pharma 24 Twin-Screw Granulator (TSG)
Speed
10-1000 rpm
Price (USD)
Full specifications
Heating Zones1 cooling zone standard. 1-2 additional cooling zones optional for up to 3 total cooling zones.
Width (Metric)Extruder W = 320mm; Cabinet W = 1200mm
Barrel4 segments for top / bottom half
Height (Metric)Extruder H = 550mm; Cabinet H = 300mm
Screw Diameter (Metric)24mm
Length (Metric)Extruder L = 2000mm; Cabinet L = 1000mm
Speed10-1000 rpm
Temperature (Metric) OperatingOperating temperature range 10…80 °C External temperature range (chiller) 5…0 °C (below 10 °C eventually condensation)
Throughput70 kg/h (depending on formulation)
DescriptionPharma 24 Twin-Screw Granulator (TSG)
Max. Torque36Nm (18Nm / shaft)
Item DescriptionATEX - upon request
Weight (Metric)Extruder = 265kg; Cabinet = 180kg
Power SupplyMain supply / frequency 3 x 400 V / N / PE, 50/60 Hz @32 A
Ambient Temperature10…40°C
Relative HumidityMax. 80% at 31°C (50% at 40°C)
Cooling SystemChiller connections In / output: G1/2 in.
Unit SizeEach
Showing 1 of 1
Catalog NumberSpecificationsUnit SizeDescriptionSpeedPrice (USD)
553-4040Full specifications
EachPharma 24 Twin-Screw Granulator (TSG)10-1000 rpmRequest A Quote
Heating Zones1 cooling zone standard. 1-2 additional cooling zones optional for up to 3 total cooling zones.
Width (Metric)Extruder W = 320mm; Cabinet W = 1200mm
Barrel4 segments for top / bottom half
Height (Metric)Extruder H = 550mm; Cabinet H = 300mm
Screw Diameter (Metric)24mm
Length (Metric)Extruder L = 2000mm; Cabinet L = 1000mm
Speed10-1000 rpm
Temperature (Metric) OperatingOperating temperature range 10…80 °C External temperature range (chiller) 5…0 °C (below 10 °C eventually condensation)
Throughput70 kg/h (depending on formulation)
DescriptionPharma 24 Twin-Screw Granulator (TSG)
Max. Torque36Nm (18Nm / shaft)
Item DescriptionATEX - upon request
Weight (Metric)Extruder = 265kg; Cabinet = 180kg
Power SupplyMain supply / frequency 3 x 400 V / N / PE, 50/60 Hz @32 A
Ambient Temperature10…40°C
Relative HumidityMax. 80% at 31°C (50% at 40°C)
Cooling SystemChiller connections In / output: G1/2 in.
Unit SizeEach
Showing 1 of 1
The Pharma 24 dedicated TSG provides maximum process flexibility through many features:
  • Horizontally split extruder barrel for easy access and cleaning
  • Easy-to-operate clamp shell design
  • Removable top and bottom liners, made from pharma grade steel
  • Main port with availability for 5 additional multi-purpose, top feed/injection ports
  • Flexible base for stand-alone operation or easy adaption to existing downstream equipment at an existing production site

Optimal design for challenging environments
The Pharma 24 TSG can set up with an optional design to operate in challenging environments. The liquid temperature control of the TSG barrel ranges from 20°C to 80°C without any electrical heating. The instrument can be set up with 1-3 cooling zones when intensive cooling of the barrel is necessary.

Maximum control and connectivity
For the best possible process control, sensors such as temperature sensors or optional process analytical technology (PAT) sensors can be used with the Pharma 24 TSG. The Pharma 24 TSG is operated from a touch panel on a movable frame, and TCP/IP can be used to integrate it into an existing overarching IT architecture. Maximum user control is delivered via five different user levels with password protection and comprehensive reporting.