Invitrogen™

PIK3CB/PIK3R2 (p110 beta/p85 beta) Recombinant Human Protein

Catalog number: A31084
Invitrogen™

PIK3CB/PIK3R2 (p110 beta/p85 beta) Recombinant Human Protein

Catalog number: A31084
Catalog Number
A31084
Unit Size
20 µg
Price (USD)
Price: 780.00
Your Price:
Availability
-
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
Price: 2,255.00
Your Price:
Availability
-
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
Price: 7,010.00
Your Price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
A3108420 µg
Price: 780.00
Your Price:
-
A32910100 µg
Price: 2,255.00
Your Price:
-
A333951 mg
Price: 7,010.00
Your Price:
-
Product Overview
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This PIK3CB/PIK3R2 (p110 beta/p85 beta) recombinant human protein (full length) was expressed in insect cells. PIK3CB/PIK3R2 lipid kinase (p110 beta/p85 beta) or Phosphatidylinositol 3-kinase (PI3K) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids which functions in signaling pathways that regulate cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kDa catalytic subunit and a 85-kDa adaptor subunit. PIK3CB plays a critical role in regulating the formation and stability of alpha-2B-beta-3 integrin adhesion bonds, which are necessary for shear force-induced platelet activation. PIK3CB sustains alpha-2B-beta-3 integrin activation and stabilized platelet aggregation by regulating both integrin-dependent calcium flux and Gi activation of RAP1B. PIK3CB/PIK3R2 (p110 beta/p85 beta) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the Adapta™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

Specifications

Accession Number
PIK3CB: NP_006210.1, PIK3R2: NP_005018.1
Molecular Weight
123.7/83.5 kDa
Quantity
20 µg
KinaseFamily
PI3 Kinase
Protein Length
Full Length
Recombinant
Yes
Protein Tag
His Tag
Shipping Condition
Dry Ice
Expression System
Insect
Protein Form
Full Length, Recombinant, Active
Form
Liquid
Validated Application
Kinase Assay
Species
Human

Contents & Storage

Storage Buffer: 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol.