AXL is a chronic myelogenous leukemia-associated oncogene that is also associated with colon cancer and melanoma. The AXL protein is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6, and is involved in the stimulation of cell proliferation.
The purified recombinant protein can be used in a number of different applications, but it has been specifically validated for use with both the LanthaScreen™ & Z'-LYTE™ assay technologies to identify novel kinase inhibitors. AXL is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the LanthaScreen & Z'-LYTE assay technology • Available in multiple pack sizes for convenient use • Also available in our SelectSceen Kinase Profiling Service
AXL Kinase Family
473 - end
Recombinant, Active, Cytoplasmic, Truncated
Contents & Storage
Storage Buffer: 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.2 mM DTT, 25% glycerol
Store at -80°C. Upon first use, aliquot and store at -80°C to avoid multiple freeze/thaws.