Invitrogen™

EGFR (ErbB1) C797S Recombinant Human Protein

Catalog number: A33722
Invitrogen™

EGFR (ErbB1) C797S Recombinant Human Protein

Catalog number: A33722
Catalog Number
A33722
Unit Size
1 mg
Price (USD)
Price: 7,010.00
Your Price:
Availability
-
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
Price: 2,255.00
Your Price:
Availability
-
Quantity
Catalog Number
Unit Size
10 µg
Price (USD)
Price: 481.00
Your Price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
A337221 mg
Price: 7,010.00
Your Price:
-
A33553100 µg
Price: 2,255.00
Your Price:
-
A3349910 µg
Price: 481.00
Your Price:
-
Product Overview
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FAQ
Citations & References
Additional Information
Recommendations
Recommendations
This EGFR (ErbB1) C797S recombinant human protein (695–end) was expressed in insect cells. EGFR receptor tyrosine kinase is a transmembrane glycoprotein. Binding of epidermal growth factor to EGFR induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation, differentiation, motility, and cell survival. Activation of EGFR triggers mitogenic signaling in gastrointestinal mucosa, and its expression is upregulated in colon cancers and most neoplasms. Activation of EGFR triggers activation of the ERK-signaling pathway in normal gastric epithelial and colon cancer cell lines. Inactivation of EGFR with selective inhibitors significantly reduces ERK2 activation, c-fos mRNA expression and cell proliferation. EGFR (ErbB1) C797S recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the Z’-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

Specifications

Accession Number
NP_005219.2
Molecular Weight
84.1 kDa
Quantity
1 mg
KinaseFamily
EGF Receptors (ErbBs)
Protein Length
aa 695 - end
Recombinant
Yes
Protein Tag
GST Tag
Shipping Condition
Dry Ice
Expression System
Insect
Protein Form
Recombinant, Active, Cytoplasmic, Mutant
Form
Liquid
Validated Application
Kinase Assay
Species
Human

Contents & Storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol