Thermo Scientific™

Exactive™ Plus EMR Orbitrap™ LC-MS System

Catalog number: IQLAAEGAAPFALGMBDL
Thermo Scientific™

Exactive™ Plus EMR Orbitrap™ LC-MS System

Catalog number: IQLAAEGAAPFALGMBDL

While analysis of denatured proteins may be the most common LC/MS protein analysis, many biopharmaceutical and biological research applications require analysis of proteins in their native (intact) state. The Thermo Scientific™ Exactive™ Plus EMR mass spectrometer combines unsurpassed high-resolution accurate-mass Thermo Scientific™ Orbitrap™ analysis with an extended mass range (EMR) option to create an outstanding tool for investigating the structure, topology, and architecture of native-like tertiary and quaternary protein structures.

 
Catalog Number
IQLAAEGAAPFALGMBDL
Unit Size
Each
Description
Exactive Plus EMR Orbitrap Mass Spectrometer
Price (USD)
Full specifications
Mass Range350 to 20,000 m/z
TypeOrbitrap LC-MS
Dynamic Range>5000:1 in. Single Scan, Intrascan Dynamic Range
Mass Accuracy<5ppm for m/z 6001 to 10,000
Polarity SwitchingOne Full Cycle in <1s (one full scan positive mode and one full scan negative mode) at resolution 35,000 at m/z 200
SensitivityIn Full-Scan MS Mode: 500 fg Buspirone on-Column S/N 100:1 Acquired with H-ESI II Probe
Item DescriptionExactive Plus EMR Orbitrap Mass Spectrometer
DescriptionExactive Plus EMR Orbitrap Mass Spectrometer
Unit SizeEach
Showing 1 of 1
Catalog NumberSpecificationsUnit SizeDescriptionPrice (USD)
IQLAAEGAAPFALGMBDLFull specifications
EachExactive Plus EMR Orbitrap Mass SpectrometerRequest A Quote
Mass Range350 to 20,000 m/z
TypeOrbitrap LC-MS
Dynamic Range>5000:1 in. Single Scan, Intrascan Dynamic Range
Mass Accuracy<5ppm for m/z 6001 to 10,000
Polarity SwitchingOne Full Cycle in <1s (one full scan positive mode and one full scan negative mode) at resolution 35,000 at m/z 200
SensitivityIn Full-Scan MS Mode: 500 fg Buspirone on-Column S/N 100:1 Acquired with H-ESI II Probe
Item DescriptionExactive Plus EMR Orbitrap Mass Spectrometer
DescriptionExactive Plus EMR Orbitrap Mass Spectrometer
Unit SizeEach
Showing 1 of 1

Confidently Identify, Characterize, and Quantify Intact Proteins

  • Extended m/z 350–20,000 mass range enables analysis of larger proteins, antibodies, antibody-drug conjugates, glycoforms, and protein assemblies
  • Improved transmission of higher-mass ions provides stronger signals
  • Resolving power up to 140,000 FWHM enables separation of isoforms and determination of glycosylation states
  • Excellent mass accuracy ensures confident identification
  • Access to short transients improves signal-to-noise ratios
  • Compatibility with Thermo Scientific Protein Deconvolution software designed specifically for identification and characterization of intact proteins

Easy-to-Use

  • Modified HCD cell controls make it easier to optimize experimental conditions
  • Intuitive operating software reduces learning curves

For Research Use Only. Not for use in diagnostic procedures.