GeneBLAzer® FPRL-1-Gα15-NFAT-bla CHO-K1 cells contain the human Formyl Peptide Like Receptor 1 (FPRL-1) stably integrated into the GeneBLAzer® Gα15-NFAT-bla CHO-K1 cell line. GeneBLAzer® Gα15-NFAT-bla CHO-K1 cells (Cat. no. K1537) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element and the Promiscuous G protein, Gα15.
The GeneBLAzer® FPRL-1-Gα15-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of W Peptide. In addition, GeneBLAzer® FPRL-1-Gα15-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
The FPRL-1 receptor has been implicated in a variety of inflammation and neurological disorders, including Alzheimer's disease.
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