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Thermo Scientific™

GeneBLAzer™ TRβ-UAS-bla HEK 293T Cells

Catalog number: K1686
Thermo Scientific™

GeneBLAzer™ TRβ-UAS-bla HEK 293T Cells

Catalog number: K1686
Catalog Number
Unit Size
2 x 106 cells
Price (USD)
Price: 8,610.00
Your Price:
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
K16862 x 106 cells
Price: 8,610.00
Your Price:
Product Overview
Citations & References
Additional Information
TR beta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Thyroid hormone receptor beta(TR beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer®UASbla HEK 293T cell line. GeneBLAzer®UAS-bla HEK 293T cells stably express a betalactamase reporter gene under the transcriptional control of an upstream activator sequence (UAS). When an agonist binds to the LBD of the GAL4 (DBD)-TR beta (LBD) fusion protein, the protein binds to the UAS, resulting in expression of beta-lactamase. Division Arrested (DA) cells are available in two configurations- an Assay Kit (which includes cells and sufficient substrate to analyze 1 x 384-well plate), and a tube of cells sufficient to analyze 10 x 384-well plates. TR beta-UAS-bla HEK 293T cells are functionally validated for Z' and EC50 concentrations of T3 Thryoid hormone. In addition, TR beta-UAS-bla HEK 293T cells have been tested for assay performance under variable conditions, including DMSO concentration, cell number, stimulation time, and substrate loading time (data available upon request). Additional testing data using alternate stimuli are also available.


Alternate Agonists
9-cis-retinoic acid, AM580
Assay Entry
Cell-based beta lactamase reporter gene
Cell State
Dividing Cells
Detection Method
Druggable Target
Nuclear Receptors
Primary Agonist
All-trans-retinoic acid (ATRA)
Product Line
Reporter Gene
BLA (Beta-Lactamase)
System Type
Target Entry
T3RB, TR beta, THRB, NR1A2
HEK 293T Cell

Contents & Storage

Shipping: Dry IceStorage: -80°C/Liquid NitrogenContains: TR beta-UAS-bla HEK 293T cells (K1248)