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RAF1 (cRAF) [Y340D] [Y341D] Recombinant Human Protein

Catalog number: PR7307A

RAF1 (cRAF) [Y340D] [Y341D] Recombinant Human Protein

Catalog number: PR7307A
Catalog Number
PR7307A
Unit Size
100 µg
Price (USD)
Price: 1,646.00
Your Price:
Availability
-
Quantity
Catalog Number
Unit Size
10 µg
Price (USD)
Price: 483.00
Your Price:
Availability
-
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
Price: 7,010.00
Your Price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PR7307A100 µg
Price: 1,646.00
Your Price:
-
PV380510 µg
Price: 483.00
Your Price:
-
PV40461 mg
Price: 7,010.00
Your Price:
-
Product Overview
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FAQ
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Additional Information
Recommendations
Recommendations
RAF1 (cRAF) is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated RAF1 can phosphorylate and activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylates and activates the serine⁄threonine specific protein kinases ERK1 and ERK2. The RAF1 Y340D Y341D mutant is constitutively active.

Specifications

Accession Number
NP_002871, Y340D, Y341D
Molecular Weight
66.4 kDa
Quantity
100 µg
Gene Alias
RAF1 (cRAF) Y340D Y341D
KinaseFamily
RAF Kinase Family
Recombinant
Yes
Protein Tag
GST Tag
Kinase Group
Ser⁄Thr Kinases: TKL Group
Shipping Condition
Dry Ice
Expression System
Baculovirus
Protein Form
Catalytic
Form
Frozen
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Development

Contents & Storage

Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.