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CSK is a tyrosine kinase that has been shown to downregulate the activity of SRC oncoprotein through phosphorylation of its carboxy terminus. Since cell transformation by SRC is caused by various mechanisms that interfere with this phosphorylation, the CSK gene might function as an antioncogene.
CSK Kinase Family
Contents & Storage
Storage Buffer: 50 mM Tris, pH 7.5, 100 mM NaCl, 10% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.