CDK5 plays a critical role in neuron development. The disregulation of the CDK5 and the truncated activator p25 is believed to be involved in neurodegenerative diseases such as Alzheimer's, Parkinson's, and Amyotrophic Lateral Sclerosis. This protein is coexpressed and copurified with p25.
NP_004926.1 I NP_003876
CDK and CHK Kinase Family
GST Tag, His Tag
Biochemical binding/kinetic, Biochemical phospho-specific activity (no antibody)
Ser⁄Thr Kinases: CMCG Group
cyclin-dependent kinase 5
Kinases & Inhibitors
Full Length, Recombinant
Cell Cycle & Proliferation, Signal Transduction
Contents & Storage
Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.