Thermo Scientific™

KIT [D820E] Recombinant Human Protein

Catalog number: PV6308
Thermo Scientific™

KIT [D820E] Recombinant Human Protein

Catalog number: PV6308
Catalog Number
PV6308
Unit Size
100 µg
Price (USD)
Price: 1,650.00
Your Price:
Availability
-
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
Price: 7,380.00
Your Price:
Availability
-
Quantity
Catalog Number
Unit Size
10 µg
Price (USD)
Price: 481.00
Your Price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV6308100 µg
Price: 1,650.00
Your Price:
-
PV63091 mg
Price: 7,380.00
Your Price:
-
PV630710 µg
Price: 481.00
Your Price:
-
Product Overview
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Additional Information
Recommendations
Recommendations
KIT (c-KIT) is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth. Recombinant human KIT D820E (544-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen® Eu Kinase Binding Assay

Specifications

Format
Kit
Molecular Weight
75.3 kDa
Quantity
100 µg
Gene Alias
PBT, SCFR, CD117
Protein Length
aa 544-end
Recombinant
Yes
Protein Tag
GST Tag
Kinase Group
Receptor Tyrosine Kinase
Expression System
Baculovirus
Protein Form
Recombinant
Form
Liquid
Validated Application
Kinase Assay
Species
Human

Contents & Storage

Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.