Thermo Scientific™

RIPK3 Recombinant Human Protein

Catalog number: PV6399
Thermo Scientific™

RIPK3 Recombinant Human Protein

Catalog number: PV6399
Catalog Number
PV6399
Unit Size
1 mg
Price (USD)
Price: 7,380.00
Your Price:
Availability
-
Quantity
Catalog Number
Unit Size
10 µg
Price (USD)
Price: 483.00
Your Price:
Availability
-
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
Price: 1,650.00
Your Price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV63991 mg
Price: 7,380.00
Your Price:
-
PV639710 µg
Price: 483.00
Your Price:
-
PV6398100 µg
Price: 1,650.00
Your Price:
-
Product Overview
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FAQ
Citations & References
Additional Information
Recommendations
Recommendations
RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, which contains a C-terminal domain unique from other RIP family members. RIPK3 is predominantly localized to the cytoplasm, and specifically, are colocalized in the mitochondrion which can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. RIPK3 is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor and caspase-8 prevents RIPK3-dependent necrosis without inducing apoptosis by functioning in a proteolytically active complex with CFLAR and that this complex is required for the protective function. Recombinant full-length human RIPK3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen® Eu Kinase Binding Assay

Specifications

Molecular Weight
83.2 kDa
Quantity
1 mg
Gene Alias
RIP3
Recombinant
Yes
Protein Tag
GST Tag
Kinase Group
Serine/Threonine Kinase
Expression System
Baculovirus
Protein Form
Recombinant
Form
Liquid
Validated Application
Kinase Assay
Species
Human

Contents & Storage

Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.