Thermo Scientific™

Perfluoroacylimidazoles (TFAI and HFBI) Acylation Reagents

Catalog number: TS-44211
Thermo Scientific™

Perfluoroacylimidazoles (TFAI and HFBI) Acylation Reagents

Catalog number: TS-44211
Conduct acylation of hydroxyl groups and primary and secondary amines with the Thermo Scientific™ Perfluoroacylimidazoles (TFAI and HFBI). Compared to acid chlorides and anhydrides, the reactions of fluorinated acylimidazoles are smooth and quantitative, and produce no acid byproducts. The principal byproduct is imidazole, which is relatively inert. The volatile and stable fluoroacyl derivatives are ideal for FID and electron-capture detection (ECD) techniques.
 
Catalog Number
TS-44211
Unit Size
Each
Standard Components
1-(2,2,3,3,4,4,4-Heptafluoro-1-oxobutyl)-1 H-imidazole
Price (USD)
Full specifications
Storage-20°C
For Use WithFID and ECD
Quantity5 g
Standard Components1-(2,2,3,3,4,4,4-Heptafluoro-1-oxobutyl)-1 H-imidazole
HazardsCombustible, Irritant
Standard Concentration98 to 100%
Item DescriptionHFBI; 5 g
Unit SizeEach
Catalog Number
Unit Size
Each
Standard Components
1-(Trifluoroacetyl)-1 H-imidazole
Price (USD)
Full specifications
Storage2°C to 8°C
For Use WithFID and ECD
Quantity10 x 1 mL Ampules
Standard Components1-(Trifluoroacetyl)-1 H-imidazole
HazardsCorrosive, Flammable
Standard Concentration98 to 100%
Item DescriptionTFAI; 10 x 1 mL ampules
Unit SizeEach
Showing 2 of 2
Catalog NumberSpecificationsUnit SizeStandard ComponentsPrice (USD)
TS-44211Full specifications
Each1-(2,2,3,3,4,4,4-Heptafluoro-1-oxobutyl)-1 H-imidazoleContact Us ›
Storage-20°C
For Use WithFID and ECD
Quantity5 g
Standard Components1-(2,2,3,3,4,4,4-Heptafluoro-1-oxobutyl)-1 H-imidazole
HazardsCombustible, Irritant
Standard Concentration98 to 100%
Item DescriptionHFBI; 5 g
Unit SizeEach
TS-48882Full specifications
Each1-(Trifluoroacetyl)-1 H-imidazoleRequest A Quote
Storage2°C to 8°C
For Use WithFID and ECD
Quantity10 x 1 mL Ampules
Standard Components1-(Trifluoroacetyl)-1 H-imidazole
HazardsCorrosive, Flammable
Standard Concentration98 to 100%
Item DescriptionTFAI; 10 x 1 mL ampules
Unit SizeEach
Showing 2 of 2
Applications

Used in bifunctional derivatization schemes and in exchange reactions in which TMS derivatives are converted to HFB derivatives.

Hydroxyl groups of catecholamines are derivatized with TMSI, followed by conversion of the amines to acylamides with HFBI.

Tryptamine and metabolites present in spinal fluid have been analyzed by ECD using HFBI.

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