Silylation Reagents

Silylation Reagents

Solutions of various chemical compositions formulated for use in mass spectrometric compound analyses via the process of silylation. Multiple reagent quantities are available.
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1-13 of 13 Products

MTBSTFA and MTBSTFA + 1% TBDMCS Silylation Reagent Thermo Scientific™

Produce stable TBDMS derivatives for GC analysis with the Thermo Scientific™ MTBSTFA and MTBSTFA + 1% TBDMCS Silylation Reagent. MTBSTFA derivatizes hydroxyl, carboxyl, thiol and primary and secondary amines with typically >96% yields, and the reaction byproducts are volatile and neutral.

Tri-Sil HTP (HDMS:TMCS:Pyridine) Reagent Thermo Scientific™

Employ a reagent-catalyst solvent mixture, for one-step derivatization with the Thermo Scientific™ Tri-Sil HTP (HDMS:TMCS:Pyridine) Reagent, Composed of HMDS, TMCS and high-purity pyridine, it rapidly produces TMS derivatives of polar compounds for GC analysis and biochemical synthesis.

BSA Silylation Reagent Thermo Scientific™

Derivatize analytes quickly and quantitatively under mild conditions using Thermo Scientific™ BSA Silylation Reagent. This reagent reacts readily with a wide range of compounds, including alcohols, amines, carboxylic acids, phenols, steroids, biogenic amines, and alkaloids to form volatile, stable...

Tri-Sil TBT (TMSI:BSA:TMCS) Reagent Thermo Scientific™

Employ a catalyzed silylation reagent formulation, for derivatization of hydroxyls with the Thermo Scientific™ Tri-Sil TBT (TMSI:BSA:TMCS) Reagent. Composed of TMSI/BSA/TMCS (3:3:2), this catalyzed silylation reagent formulation typically reacts with hydroxyls in a short period of time at 60–80 °C...

MSTFA and MSTFA + 1% TMCS Silylation Reagent Thermo Scientific™

Use Thermo Scientific™ MSTFA and MSTFA + 1% TMCS Silylation Reagent for GC analyses of early eluting compounds that would otherwise be obscured in the chromatogram. MSTFA, the most volatile TMS-amide available, and its byproduct N-methyltrifluoroacetamide typically elute with the solvent front,...

Tri-Sil TP (TMSI:Pyridine) Reagent Thermo Scientific™

Derivatize hydroxyls compounds, particularly carbohydrates with Thermo Scientific™ Tri-Sil TP (TMSI:Pyridine) Reagent. Comprising TMSI in pyridine, this reagent silylates alcohols and phenols, organic acids, hydroxylamines, amino acids, carbohydrates, flavonoids, glycols and polyglycols,...

BSTFA + 1% TMCS Silylation Reagent Thermo Scientific™

Use Thermo Scientific™ BSTFA + 1% TMCS Silylation Reagent for analytes that are difficult to silylate. Stronger than BSTFA alone, this catalyzed formulation is ideal for derivatizing compounds such as fatty acid amides and slightly hindered hydroxyls for GC analysis.

Tri-Sil BP (BSA:Pyridine) Reagent Thermo Scientific™

Employ a reagent-solvent mixture, for one-step derivatization with the Thermo Scientific™ Tri-Sil BP (BSA:Pyridine) Reagent, Composed of BSA and high-purity pyridine, this silylation reagent formulation derivatizes alcohols, phenols, organic acids, aromatic amides, and amines for GC analysis.

TMCS Silylation Reagent Thermo Scientific™

Catalyze the derivatization of difficult-to-silylate compounds using Thermo Scientific™ TMCS Silylation Reagent. It is an excellent adjunct for forming TMS ethers for GC determinations. TMCS is also useful for preparing TMS derivatives of organic acids.

BSTFA Silylation Reagent Thermo Scientific™

Improve GC analysis with Thermo Scientific™ BSTFA Silylation Reagent. The highly volatile byproducts mono(trimethylsilyl)trifluoroacetamide (BSTFA) and trifluoroacetamide elute with the solvent front to ensure excellent chromatographic separations.

HMDS (Hexamethyldisilazane) Thermo Scientific™

Thermo Scientific™ HMDS (Hexamethyldisilazane) greatly extends the practical range of GC, improving chromatographic results in the silylation of sugars and related substances.

TMSI Silylation Reagent Thermo Scientific™

Employ the strongest silylator available for carbohydrates and steroids with the Thermo Scientific™ TMSI Silylation Reagent. This silylation reagent reacts quickly with hydroxyls and carboxylic acids but not with amines, and is particularly well suited in multiderivatization schemes for compounds...

Methoxamine (MOX) Reagent Thermo Scientific™

Prepare oximes of steroids and ketoacids prior to silylation with the Thermo Scientific™ Methoxamine (MOX) Reagent. It prevents the formation of multiple derivatives when enols are present during silylation, thereby ensuring optimal quantitation.
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