Thermo Fisher Scientific
The emergence of novel psychoactive substances (NPS) is an ongoing challenge for forensic toxicologists. Different analogs are continuously introduced in the market to circumvent legislation and to enhance their pharmacological activity.
At the National Institute on Drug Abuse (NIDA), Dr Concheiro has developed two analytical methods for the determination of new psychoactive stimulants in urine by liquid chromatography–high resolution mass spectrometry with Orbitrap technology.
One method identified and quantified 28 synthetic cathinones by targeted-MSMS experiments. In the second method, 8 piperazines, 4 designer amphetamines and 28 synthetic cathinones and 4 metabolites were analyzed in full scan and data dependent MS mode. Both methods were sensitive (limit of quantification 0.5-5 ng/mL) and specific, fully validated and applied to authentic cases.
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Marta Concheiro, Assistant Professor of Forensic Toxicology, John Jay College
Marta Concheiro is Assistant Professor of Forensic Toxicology at John Jay College of Criminal Justice, City University of New York. Currently her research is focused on the study of alternative matrices in forensic and clinical toxicology (oral fluid, hair, umbilical cord) and in the investigation of novel psychoactive substances.
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