Part 1: A Short Journey to Bio/Pharmaceutical UHPLC Method Transfer Success

Transferring bio/pharmaceutical ultra-high performance liquid chromatography (UHPLC) methods between UHPLC systems in the same lab, between labs or to an external partner lab can be challenging. Join Dr. Frank Steiner from (Thermo Fisher Scientific) and Dr. Dan Bach Kristensen (from Symphogen) as they take you on a journey of UHPLC method transfer-you may be surprised how short it can be. Comprehensive insights will be provided into the critical parameters that should be considered when transferring methods between UHPLC systems of the same or differing type. Real-world examples from the biopharmaceutical industry will be shared.

About the presenters

Dr. Frank Steiner, Senior Manager HPLC Applications Development & Scientific Advisor, Thermo Fisher Scientific

Dr. Steiner will discuss how you can achieve equivalent results between UHPLC systems to become operational as quickly as possible with minimal revalidation efforts. Hear recommendations on how to modify parameters to obtain equivalent results, with respect to USP General Chapter <621> Chromatography, and how you can characterize the root cause for common method transfer problems.

Dr. Dan Bach Kristensen, Principal Scientist, Symphogen

Dr. Kristensen will share his experience with the Thermo Scientific Vanquish UHPLC platform and experiences of performing complex biopharmaceutical separations between UHPLC systems within one site and in the laboratory of an external partner.