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        Latest Mass Spectrometry-based Trends for Identifying and Quantifying Unknown PFAS Compounds

        In the state of North Carolina, the NC Policy Collaborator formed a PFAST Network, comprised of many university scientists whose goal it is to monitor PFAS compounds in public drinking water supplies. The PFAST network takes both an untargeted and targeted analytical approach to perform testing, with the former approach focused on identifying previously unknown and potentially toxic compounds. Given the importance of identifying new toxic PFAS compounds, performing small molecule unknown analysis can become quite a daunting task. One of the laboratories that is part of the PFAST network is the Ferguson Laboratory at Duke University.

        In this webinar, Drs. Lee Ferguson and Abigail Joyce discuss a Thermo Scientific Orbitrap Mass Spectrometer-based method used to demystify unknown PFAS compounds in drinking water.

        About the presenters

        Lee Ferguson, Associate Professor, Duke University

        Lee Ferguson, Associate Professor, Duke University

        Lee Ferguson, Ph.D., is Associate Professor of Civil and Environmental Engineering at Duke University. Research in the Ferguson laboratory is focused on development of novel methods for trace analysis of organic and nanoparticulate contaminants in the aquatic environment.

        Abigail Joyce, Research Scientist, Duke University

        Abigail Joyce, Research Scientist, Duke University

        Abigail Joyce, Ph.D., is Manager of the Analytical Chemistry Core and Research Scientist in Dr. Ferguson’s laboratory at Duke University. Her goals are to provide high quality analytical analysis and develop new analytical methods to keep up with the university’s research needs.

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        Resources

        • Direct analysis of selected per- and polyfluorinated alkyl substances (PFAS) in ground, surface, and waste water by LC-MS/MS
        • Secondary validation study for EPA Method 537.1 using automated SPE followed by LC-Q Exactive Orbitrap MS
        • AquireX intelligent data acquisition technology for orbitrap tribrid mass spectrometers – collect more meaningful data, not just more data
        • Transitioning to confident quantitation— in search of a better tomorrow
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