Sign in
Don't have an account ? Create Account
  • Products
    • Antibodies
    • Oligos, Primers, Probes and Genes
    • TaqMan Real-Time PCR Assays
    • Cell Culture Media
    • Chemicals
    • Chromatography Columns and Cartridges
    • Lab Equipment
    • Lab Plasticware and Supplies
    • Microplates
    • Tubes
    • See all product categories
  • Applications
    • Bioprocessing
    • Cell Culture and Transfection
    • Cell and Gene Therapy
    • Chromatography
    • Clinical Genomics
    • Digital Solutions
    • DNA and RNA Extraction and Analysis
    • Spectroscopy, Elemental and Isotope Analysis
    • See all applications and techniques
  • Services
    • CDMO & Clinical Trial Services
    • Custom Services
    • Enterprise Services
    • Financial & Leasing Services
    • Instrument Services
    • Lab Informatics
    • OEM & Commercial Supply
    • Training Services
    • Unity Lab Services
    • See all services
  • Help and Support
    • Register for an Account
    • How to Order
    • Instrument Support
    • Technical Support Centers
    • Learning Centers
    • See all help and support topics
  • Popular
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • Contact Us
  • Quick Order
  • Order Status and Tracking
  • Documents and Certificates

Search Thermo Fisher Scientific

Search All
Search button Close
        • Order Status
        • Quick Order
        • Sign in
          Sign in
          Don't have an account ? Create Account
          • Aspire Member Program
          • Connect: Lab, Data, Apps
          • Custom Products & Projects
          • Instrument Management

        Increased Confidence in Untargeted Volatile E&L Analysis by Static Headspace Sampling Coupled to HRAM GC-MS

        Pharmaceutical products come into contact with a wide range of polymeric materials on their journey from the production line to patients, with possible leaching of potentially dangerous substances into products, possibly compromising the stability, or even worse, the pharmacological activity. Extractable and leachable (E&L) compounds are the focus of rigorous testing workflows to ensure therapeutics are safe and meet regulatory requirements.

        This webcast will present an E&L study aiming to address the challenges to achieve sufficient sensitivity and selectivity for unknown analytes potentially present in the sample.

        A method has been optimized with the use of static headspace autosampling coupled with a HRAM GC–MS, resulting in a powerful technique to assess and quantify potentially dangerous untargeted volatile extractables down to trace level. Very high mass accuracy with errors of 1 ppm or better, even for smaller molecules and fragments, increases confidence in structure elucidation of unknown compounds.

        Key Learning Objectives:

        • Learn about streamlining workflow for organic volatile impurities from contact materials
        • Learn how to optimize headspace sampling parameters with a strategy based on the theory of gas phase chemistry
        • Discover the benefits of using HRAM GC–MS for untargeted or unknown impurities

        Who Should Attend:

        • Scientists, chemists, and analysts involved in E&L testing
        • Laboratory managers in the pharmaceutical industry, CMOs, CROs and contract services
        • Researchers and method developers interested in E&L methodology

        About the presenters

        Xiaotend (Shelton) Gong, Instrumentation Chemist, Extractable and Leachable (E&L) Testing, SGS

        Xiaotend (Shelton) Gong, Instrumentation Chemist, Extractable and Leachable (E&L) Testing, SGS

        Xiaoteng Gong received his Master’s degree from the Illinois Institute of Technology, and has worked on food contact materials at the National Center for Food Safety and Technology (NCFST) of the Food and Drug Administration (FDA). With extensive experience in analytical chemistry, he currently is an instrumentation chemist at SGS specializing in extractables and leachables (E&L) studies for pharmaceutical packaging. He has more than five years of experience using headspace gas chromatography–mass spectrometry (GC–MS).

        Daniela Cavagnino, Marketing Manager, GC-MS, Thermo Fisher Scientific

        Daniela Cavagnino, Marketing Manager, GC-MS, Thermo Fisher Scientific

        Daniela Cavagnino received a Master’s degree in Chemistry from the University of Milan, Italy. She started her career in gas chromatography at Thermo Fisher Scientific, spending several years in the R&D laboratories working on GC technology innovation. Then, she conveyed her technical background into product management and marketing management roles, and she now has more than 15 years of experience promoting GC and GC–MS technology and applications in several different market segments. During her career, she has participated as an author and co-author in technical publications and as a lecturer at international conferences.

        Fill out the form to view the free
        on-demand webinar

        * Required field

        *
        *
        *
        *
        *
        *
        *
        *
        *
        *

         I would like to speak with an expert to learn how Thermo Fisher Scientific products can help in my laboratory
         Please confirm you would like to receive marketing and promotional email messages about Thermo Fisher Scientific products and services.
         
         
        OrderingPlus Icon Minus Icon
        • Order Status
        • Order Help
        • Quick Order
        • Supply Center
        • eProcurement
        SupportPlus Icon Minus Icon
        • Help and Support
        • Contact Us
        • Technical Support Centers
        • Documents and Certificates
        • Report a Site Issue
        ResourcesPlus Icon Minus Icon
        • Learning Centers
        • Promotions
        • Events and Webinars
        • Social Media
        About Thermo FisherPlus Icon Minus Icon
        • About Us About Us
        • Careers Careers
        • Investors Investors
        • News News
        • Social Responsibility Social Responsibility
        • Trademarks
        Our PortfolioPlus Icon Minus Icon
        • Thermo Scientific
        • Applied Biosystems
        • Invitrogen
        • Gibco
        • Ion Torrent
        • Fisher Scientific
        • Unity Lab Services
        • Patheon
        • PPD
        • Terms & Conditions
        • Privacy Information Center
        • Price & Freight Policy
        © Copyright 2006-2023 Thermo Fisher Scientific Inc. All rights reserved
        United States flag icon
        United States
        Sign in
        Don't have an account ? Create Account
        • Aspire Member Program
        • Connect: Lab, Data, Apps
        • Custom Products & Projects
        • Instrument Management