No-Fail SureStop Screw Vials & AVCS Caps

An optimal screw top seal every time

Prevent screw thread vial failures such as cap tilt, cap deformities, dislodged septa or septum push through. Thermo Scientific SureStop Vials and Advanced Vial Closure System (AVCS) caps are specially designed to:

  • Properly seal every time
  • Significantly reduce re-analysis
  • Increase sample throughput
  • Reduce solvent/sample evaporation
  • Maintain sample/data integrity
  • Provide an alternative to crimp, snap, and bonded caps
  • Works with both LC and GC instruments

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Thermo Scientific SureStop screw thread vials, AVCS caps, and kits

9mm SureStop Vials

SureStop vials are designed as part of the Advance Vial Closure System (AVCS) and remove any subjectivity around achieving the optimal seal compression when closing a vial. Below are 2mL, 12x32mm vials in clear and amber glass with 9mm screw thread vials for use with AVCS caps to provide the ultimate in sample security

9mm SureStop Screw Top Vials
CatalogGlassMarking spotDimensionsBaseVolume (total)Vol (useable)Vol (residual)Pack of
C5000-1ClearNo12x32Flat2.0mL1.5mL<170100
C5000-1WClearYes12x32Flat2.0mL1.5mL<170100
C5000-2AmberNo12x32Flat2.0mL1.5mL<170100
C5000-2WAmberYes12x32Flat2.0mL1.5mL<170100
2-SVWGKClear
Gold
Grade		Yes12x32Flat2.0mL1.5mL<170100
2-SVWK(A)AmberYes12x32Flat2.0mL1.5mL<170100
9mm AVCS Cap-Septum Combination Seals

The 9mm AVCS closures (C5000- and K-series) complement SureStop vials and are based on Thermo Scientific Advance Vial Closure System (AVCS), designed to overcome challenges associated with 9mm closures. It features a completely redesigned septa/cap interface that is designed to virtually eliminate septa push-through while improving sealing. Thermo Scientific in-house testing has also shown reduced evaporation compared to all other 9mm closures. In addition, the increased surface area available for injection provides compatibility with a broader range of autosamplers than previous designs.

As with any vial cap, choose the preferred cap color (black, blue, red, green, yellow, pink, white, grey, or transparent) paired with the septum that is compatible with your autosampler needle (gauge and tip form) and solvent. The softer the septum, the thinner the needle can be. Sealing and re-sealing is improved by softer septa. Harder septa have no “trampoline” effect and a sharp needle can easily penetrate the septa with little resistance.

9 mm AVCS Caps and Septum Combination Seals

CatalogCap colorCap materialSeptumHardnessThicknessPack of
9mm AVCS Open Top Screw Cap, 6mm hole
C5000-44BBluePolypropyleneSoft septum, PTFE/Blue Silicone301.0100
C5000-45BBluePolypropyleneSoft septum, PTFE/Blue Silicone, Pre-slit301.0100
9-SCK(B)-ST101BluePolypropyleneBlue Silicone/PTFE301.0500
C5000-51RedPolypropyleneIvory PTFE/Red Rubber451.0100
C5000-51YYellowPolypropyleneIvory PTFE/Red Rubber451.0100
C5000-51PPinkPolypropyleneIvory PTFE/Red Rubber451.0100
C5000-57BBluePolypropyleneIvory PTFE/Red Rubber, Pre-slit451.0100
C5000-57GGreenPolypropyleneIvory PTFE/Red Rubber, Pre-slit451.0100
C5000-64BBlackPolypropyleneBonded Red PTFE/White Silicone451.0100
C5000-75CGrayPolypropyleneBonded Red PTFE/White Silicone, Pre-slit451.0100
C5000-62BBluePolypropyleneBonded Natural PTFE/Clear Silicone451.3100
C5000-53ABlackPolypropyleneRed PTFE/White Silicone/Red PTFE501.0100
C5000-53BBluePolypropyleneRed PTFE/White Silicone/Red PTFE501.0100
C5000-53GGreenPolypropyleneRed PTFE/White Silicone/Red PTFE501.0100
C5000-53R RedPolypropyleneRed PTFE/White Silicone/Red PTFE501.0100
C5000-53YYellowPolypropyleneRed PTFE/White Silicone/Red PTFE501.0100
C5000-54ABlackPolypropyleneRed PTFE/White Silicone551.0100
C5000-54BBluePolypropyleneRed PTFE/White Silicone551.0100
C5000-54GGreenPolypropyleneRed PTFE/White Silicone551.0100
C5000-54RRedPolypropyleneRed PTFE/White Silicone551.0100
C5000-54YYellowPolypropyleneRed PTFE/White Silicone551.0100
C5000-54PPinkPolypropyleneRed PTFE/White Silicone551.0100
C5000-55ABlue PTFE/White Silicone, Pre-slitPolypropyleneBlack551.0100
C5000-55BBluePolypropyleneBlue PTFE/White Silicone, Pre-slit551.0100
C5000-55GGreenPolypropyleneBlue PTFE/White Silicone, Pre-slit551.0100
C5000-55RRedPolypropyleneBlue PTFE/White Silicone, Pre-slit551.0100
C5000-55YYellowPolypropyleneBlue PTFE/White Silicone, Pre-slit551.0100
C5000-55PPinkPolypropyleneBlue PTFE/White Silicone, Pre-slit551.0100
C5000-52AEBluePolypropyleneSolid PTFE Disk with Silicone sealing ring531.0100
9-SCK(B)-ST1 BluePolypropyleneWhite Silicone/Red PTFE571.0500
9-SCK(G)-ST1GreenPolypropyleneWhite Silicone/Red PTFE571.0500
9-SCK(N)-ST1ClearPolypropyleneWhite Silicone/Red PTFE571.0500
9-SCK(B)-ST1XBluePolypropyleneWhite Silicone/Red PTFE, Y-Pre-slit571.0500
9-SCK(B)-TST1 BluePolypropyleneRed PTFE/White Silicone/Red PTFE571.0500
9-SCK(B)-8RT1BluePolypropyleneRed Rubber/Clear PTFE581.0500
9-SCK(B)-8RT1XBluePolypropyleneRed Rubber/Clear PTFE, Pre-slit581.0500
C5000-56ALBluePolypropyleneSolid Aluminum Disk with Silicone sealing ring-0.06100
9mm AVCS Screw Cap with Integral PP Membrane
C5000-50ClearPolypropylenePolypropyleneN/AN/A100
C5000-50BBluePolypropylenePolypropyleneN/AN/A100
9-SCNKBBluePolypropylenePolypropylene  500
9mm AVCS Closed Top Screw Top Cap
C5000-99BBluePolypropyleneIvory PTFE/Red Rubber451.0100
9mm AVCS Magnetic Open Screw Top Cap, 6mm hole
C5000-46MBluePolypropyleneSoft septum, PTFE/Blue Silicone301.0100
C5000-47MBluePolypropyleneSoft septum, PTFE/Blue Silicone, Pre-slit301.0100
9-MSC(BG)-ST1Blue/GoldPP/SteelSoft septum, PTFE/Blue Silicone, Pre-slit301.0100
9-MSC(BG)-ST1Blue/GoldPP/SteelWhite Silicone/Red PTFE571.0100
9-MSC(BG)-ST101 Blue/GoldPP/SteelSoft septum, Blue Silicone/PTFE301.0100
9-MSC(BG)-ST101X Blue/GoldPP/SteelSoft septum, Blue Silicone/PTFE, Pre-slit301.0100
9mm SureStop Vial - AVCS Cap Kits

9mm Wide Opening Screw Thread Vials Convenience Kits

Kit CatalogGlassPatchCapSeptumVial Catalog /
Closure Catalog		Pack of
Unassembled Kits – SureStop vials with AVCS caps
C5000-580ClearNoBlueIvory PTFE/Red RubberC5000-1
C5000-51B		100
C5000-580WClearYesBlueIvory PTFE/Red RubberC5000-1W
C5000-51B		100
C5000-592ClearNoBlueRed PTFE/White SiliconeC5000-1
C5000-54B		100
C5000-592WClearYesBlueRed PTFE/White SiliconeC5000-1W
C5000-54B		100
C5000-586WClearYesBlueRed PTFE/White Silicone/Red PTFEC5000-1W
C5000-53B		100
C5000-595WClearYesBlueBlue PTFE/White Silicone, Pre-slitC5000-1W
C5000-55B		100
2-SVWGK8-CPKClear GOLD GRADEYesBlueRed Natural Rubber/Clear PTFE2-SVWGK
9-SCK(B)-8RT1		100
2-SVWGKST-CPKClear GOLD GRADEYesBlueWhite Silicone/Red PTFE2-SVWGK
9-SCK(B)-ST1		100
2-SVWK(A)8-CPKAmberYesBlueRed Natural Rubber/Clear PTFE2-SVWK(A)
9-SCK(B)-8RT1		100
2-SVWK(A)8-CPKAmberYesBlueRed Natural Rubber/Clear PTFE2-SVWK(A)
9-SCK(B)-8RT1		100
2-SVWK(A)ST-CPKAmberYesBlueWhite Silicone/Red PTFE2-SVWK(A)
9-SCK(B)-ST1		100
Unassembled Kits – Standard vials with AVCS caps
C5000-80ClearNoBlueIvory PTFE/Red RubberC4000-1
C5000-51B		100
C5000-80WClearYesBlueIvory PTFE/Red RubberC4000-1W
C5000-51B		100
C5000-82PAmberYesPinkIvory PTFE/Red RubberC4000-2W
C5000-51P		100
C5000-82WAmberYesBlueIvory PTFE/Red RubberC4000-2W
C5000-51B		100
C5000-83WClearYesBlueIvory PTFE/Red Rubber, Pre-slitC4000-1W
C5000-57B		100
C5000-86ClearNoBlueRed PTFE/White Silicone/Red PTFEC4000-1
C5000-53B		100
C5000-86WClearYesBlueRed PTFE/White Silicone/Red PTFEC4000-1W
C5000-53B		100
C5000-88WAmberYesBlueRed PTFE/White Silicone/Red PTFEC4000-2W
C5000-53B		100
C5000-87PolypropyleneNoBlueRed PTFE/White SiliconeC4000-11
C5000-54B		100
C5000-91WClearYesBlackRed PTFE/White SiliconeC4000-1W
C5000-54A		100
C5000-92ClearNoBlueRed PTFE/White SiliconeC4000-1
C5000-54B		100
C5000-92PClearNoPinkRed PTFE/White SiliconeC4000-1
C5000-54P		100
C5000-92WClearYesBlueRed PTFE/White SiliconeC4000-1W
C5000-54B		100
C5000-94WAmberYesBlueRed PTFE/White SiliconeC4000-2W
C5000-54B		100
C5000-95ClearNoBlueBlue PTFE/White Silicone, Pre-slitC4000-1
C5000-55B		100
C5000-95WClearYesBlueBlue PTFE/White Silicone, Pre-slitC4000-1W
C5000-55B		100
C5000-LV95ClearNoBlueBlue PTFE/White Silicone, Pre-slitC4000-LV1
C5000-55B		100
C5000-97PolypropyleneNoBlueBlue PTFE/White Silicone, Pre-slitC4000-11
C5000-55B		100
C5000-78WClearYesBlackBonded Red PTFE/White SiliconeC4000-1W
C5000-64B		100
C5000-93WClearYesGrayBonded Red PTFE/White Silicone, Pre-slitC4000-1W
C5000-75C		100
C5000-80WYClearYesYellowIvory PTFE/Red RubberC4000-1W
C5000-51Y		100
C5000-92WYClearYesYellowYellow PTFE/White SiliconeC4000-1W
C5000-54YY		100
C5000-86WYClearYesYellowYellow PTFE/White Silicone/Yellow PTFEC4000-1W
C5000-53YY		100
C5000-94WYAmberYesYellowYellow PTFE/White SiliconeC4000-2W
C5000-54YY		100
2-SVW8-CPKClearYesBlueRed Natural Rubber/Clear PTFE2-SVW
9-SCK(B)-8RT1		100
2-SVWST-CPKClearYesBlueWhite Silicone/Red PTFE2-SVW
9-SCK(B)-ST1		100
2-SVW(A)8-CPKAmberYesBlueRed Natural Rubber/Clear PTFE2-SVW(A)
9-SCK(B)-8RT1		100
2-SVW(A)ST-CPKAmberYesBlueWhite Silicone/Red PTFE2-SVW(A)
9-SCK(B)-ST1		100
Assembled Kits – Standard vials with AVCS caps
C5000-180ClearNoBlueIvory PTFE/Red RubberC4000-1
C5000-51B		100
C5000-180WClearYesBlueIvory PTFE/Red RubberC4000-1W
C5000-51B		100
C5000-182WAmberYesBlueIvory PTFE/Red RubberC4000-2W
C5000-51B		100
C5000-183WClearYesBlueIvory PTFE/Red Rubber, Pre-slitC4000-1W
C5000-57B		100
C5000-184WAmberYesBlueIvory PTFE/Red Rubber, Pre-slitC4000-2W
C5000-57B		100
C5000-186ClearNoBlueRed PTFE/White Silicone/Red PTFEC4000-1
C5000-53B		100
C5000-186WClearYesBlueRed PTFE/White Silicone/Red PTFEC4000-1W
C5000-53B		100
C5000-186WRClearYesRedRed PTFE/White Silicone/Red PTFEC4000-1W
C5000-53R		100
C5000-188WAmberYesBlueRed PTFE/White Silicone/Red PTFEC4000-2W
C5000-53B		100
C5000-186WYClearYesYellowYellow PTFE/White Silicone/Yellow PTFEC4000-1W
C5000-53YY		100
C5000-192ClearNoBlueRed PTFE/White SiliconeC4000-1
C5000-54B		100
C5000-192WClearYesBlueRed PTFE/White SiliconeC4000-1W
C5000-54B		100
C5000-194WAmberYesBlueRed PTFE/White SiliconeC4000-2W
C5000-54B		100
C5000-195WClearYesBlueBlue PTFE/White Silicone, Pre-slitC4000-1W
C5000-55B		100
C5000-196WAmberYesBlueBlue PTFE/White Silicone, Pre-slitC4000-2W
C5000-55B		100
Instrument-Specific SureStop Vials - AVCS Caps Kits

We offer the most suitable combination packs for the most popular instruments currently in use. The contents have been carefully chosen to match the needs of particular autosamplers.

Instrument-Specific Kits with Surestop vials and/or AVCS caps
Kit Designed forCatalogGlassPatchCapSeptumVial Catalog /Closure CatalogPack of
Instrument-Specific Unassembled Convenience Kits with SureStop vials and AVCS caps
Thermo GC AutosamplerTTRGKKClear GOLD GradeYesBlueBlue Silicone/PTFE2-SVWGK
9-SCK(B)-ST101		100
Instrument-Specific Unassembled Convenience Kits with standard vials and AVCS caps
Agilent LC AutosamplerHPLSKClearYesBlueRed Natural Rubber/Clear PTFE2-SVW
9-SCK(B)-8RT1		100
Thermo GC AutosamplerTTRKClearYesBlueBlue Silicone/PTFE2-SVW
9-SCK(B)-ST101		100
Varian GC Autosampler (Assembled)VAGKClearYesBlueWhite Silicone/Red PTFE2-SVW
9-SCK(B)-ST1		100
Varian LC AutosamplerVALKClearYesBlueWhite Silicone/Red PTFE2-SVW
9-SCK(B)-ST1		100
Waters Alliance® LC AutosamplerWALKClearYesBlueWhite Silicone/Red PTFE2-SVW
9-SCK(B)-ST1		100
PerkinElmer LC AutosamplerPELKClearYesGreenWhite Silicone/Red PTFE, Preslit2-SVW
9-SCK(G)-ST1X		100
Waters Alliance LC AutosamplerWALBKClearYesBlackBonded Red PTFE/White Silicone2-SVW
9-SCK(BLK)-BST1		100
SureStop Vial - AVCS Cap Storerooms
National 9mm Wide Opening Screw Thread Vial Storerooms
Kit CatalogGlassPatchCapSeptumVial Catalog /Closure CatalogPack of
9 Drawer Storeroom, 2000 pieces, SureStop vials with ACVS Caps
C5075-213ClearYesBlueRed PTFE/White Silicone/Red PTFEC5000-1W
C5000-53B 		1
C5075-219ClearNoBlueRed PTFE/White SiliconeC5000-1
C5000-54B 		1
Certified SureStop Vial - AVCS Cap Kits

Certifications become more and more important in order to make processes more reproducible and avoid possible sources of errors right from the beginning. For Thermo Scientific highest quality, consistency and quality control have always been very important and are represented by these HPLC and GC certified kits. The Certified Vial Kits are fully lot-tested including HPLC and GC analysis for 15 critical parameters. The certificate of Conformance is included in every pack.

See all Certified & MS Certified vials & closures.

HPLC & GC Certified Vial Kits (Unassembled and Assembled)

CatalogVial GlassPatchedCapSeptumVial / Closure CatalogPack of
Certified Convenience Kit (Unassembled) 9mm wide opening SureStop vials with AVCS caps
CERT5000-575W2mL AmberYesBlueRed PTFE/White SiliconeC5000-2W
C5000-54B		100
CERT5000-576W2mL AmberYesBlueBlue PTFE/White Silicone, Pre-slitC5000-2W
C5000-55B		100
CERT5000-578W2mL ClearYesBlueRed PTFE/White SiliconeC5000-1W
C5000-54B		100
CERT5000-580W2mL ClearYesBlueIvory PTFE/Red RubberC5000-1W
C5000-51B		100
CERT5000-582W2mL AmberYesBlueIvory PTFE/Red RubberC5000-2W
C5000-51B		100
CERT5000-593W2mL ClearYesBlueBlue PTFE/White Silicone, Pre-slitC5000-1W
C5000-55B		100
Certified Convenience Kit (Unassembled) 9mm wide opening standard vials with AVCS caps
CERT5000-69LV350µL Fused Insert ClearYesBlackBonded Red PTFE/White SiliconeC4000-LV1W
C5000-64B		100
CERT5000-72LV350µL Fused Insert AmberYesBlackBonded Red PTFE/White SiliconeC4000-LV2W
C5000-64B		100
CERT5000-75W2mL AmberYesBlackBonded Red PTFE/White SiliconeC4000-2W
C5000-64B		100
CERT5000-76W2mL AmberYesGrayBonded Clear PTFE/Clear Silicone, Pre-slitC4000-2W
C5000-75C		100
CERT5000-78W2mL ClearYesBlackBonded Red PTFE/White SiliconeC4000-1W
C5000-64B		100
CERT5000-791.7mL High Recovery ClearNoGray BBonded Clear PTFE/Clear Silicone, Pre-slitC4000-9
C5000-75C		100
CERT5000-802mL ClearNoBlueIvory PTFE/Red RubberC4000-1
C5000-51B		100
CERT5000-80W2mL ClearYesBlueIvory PTFE/Red RubberC4000-1W
C5000-51B		100
CERT5000-82W2mL AmberYesBlueIvory PTFE/Red RubberC4000-2W
C5000-51B		100
CERT5000-92W2mL ClearYesBlueRed PTFE/White SiliconeC4000-1W
C5000-54B		100
CERT5000-93W2mL ClearYesGrayBonded Clear PTFE/Clear Silicone, Pre-slitC4000-1W
C5000-75C		100
CERT5000-9921.7mL High Recovery ClearNoBlackBonded Red PTFE/White SiliconeC4000-9
C5000-64B		100
CERT5000-993Total Recovery Vial, w/10µL Reservoir ClearNoGrayBonded Clear PTFE/Clear Silicone, Pre-slitC4000-9TR
C5000-75C		100
Certified Kits (Assembled) 9mm wide opening standard vials with AVCS caps
CERT5000-175W2mL AmberYesBlackBonded Red PTFE/White SiliconeC4000-2W
C5000-64B		100
CERT5000-193W2mL ClearYesGrayBonded Red PTFE/ White Silicone, Pre-slitC4000-1W
C5000-75C		100
CERT5000-176W2mL AmberYesGrayBonded Red PTFE/ White Silicone, Pre-slitC4000-2W
C5000-75C		100
MS Certified SureStop Vial - AVCS Cap Kits

When your instrumentation, sample handling and methodology is pushing the limits, a chromatography vial that can keep up is essential, use the only chromatography vials pre-cleaned to provide unmatched consistency.

  • The first low particle, low background chromatography vials
  • Tested and certified for up to 15 critical physical characteristics affecting vial performance
  • Tested and certified for low background by positive ESI LC/MS and by GC/MS

See all Certified & MS Certified vials & closures.

9mm MS Certified Vial Convenience Kits (Unassembled)
CatalogVialGlass PatchedCap ColorSeptumPack of
MS Certified Convenience Kits (Unassembled) - SureStop Vials with AVCS Caps
MSCERT5000-34W 2mL SureStop Screw Vial, with AVCS Closure Clear Yes Blue Blue Silicone/PTFE 100
MSCERT5000-35W 2mL SureStop Screw Vial, with AVCS Closure Amber Yes Blue Blue Silicone/PTFE 100
MSCERT5000-40W 2mL SureStop Screw Vial, with AVCS Closure Clear Yes Blue Blue Silicone/PTFE, Pre-slit 100
MSCERT5000-41W 2mL SureStop Screw Vial, with AVCS Closure Amber Yes Blue Blue Silicone/PTFE, Pre-slit 100

Benefits of SureStop Vials – AVCS Caps

How tight should you screw your cap on the vial? How do you avoid misalignments & cap deformities? Remove all doubt by using SureStop Vials with AVCS Caps. This is why:

  1. Prevents cap misalignment
    A leveling feature in the SureStop vial design eliminates cap tilt, which can interfere with autosampler functioning, cause septa deformities, and cause sample evaporation.
  2. Ensures optimal degree of tightening, every time
    The SureStop vial finish incorporates a definite stop point that gives you positive-feedback on when the cap is optimally tightened. This eliminates overtightened or under tightened caps, which can interfere with autosampler functioning, and cause septa deformities and sample evaporation.
AVCS Corrects Misalignments
  1. SureStop/AVCS vial self-aligning cap
  2. Generic vial with cap tilt
  3. Generic vial with dislodged septum
  4. Generic vial with deformed cap
  1. Reduces autosampler interruption, increases autosampler compatibility
    Optimal vial seal compression of SureStop vial-AVCS cap combination
    1. Make vials more compatible with more autosamplers
    2. Have fewer autosampler interruptions due to mishandled vials and vial deformities
  2. Provides an alternative to crimp and snap vials, and bonded caps
    Our tested SureStop vials with AVCS caps offer the performance expected from traditional crimp vials without the need for crimping and decrimping tools. Performance tests reported in this technical note showed that there was less evaporation compared to a crimp vial. Due to the simplicity, reliability and versatility to use the SureStop/AVCS vial-cap system in both GC and LC instruments, you can understand why some customers prefer the easy-to-use SureStop/AVCS vial-cap system to crimped vials.
  • How tight should you screw your cap on the vial?
  • How to avoid misalignments & cap deformities

Not sure which vial is right for you?

Contact with an expert to help you decide.

Speak to a specialist

Resources

SureStop & AVCS vials & caps resources

CMD SchemaApp code