Porous graphitic carbon (PGC, Hypercarb™) has unique properties as a stationary phase in high-performance liquid chromatography (HPLC). Its chemical surface properties distinguish it from more conventional LC packings such as bonded-silica gels and polymers. PGC behaves as a strongly retentive alkyl-bonded silica gel for non-polar analytes.
However, its retention and selectivity behavior towards polar and structurally-related compounds is very different from conventional C18 columns.
|Property||To meet requirement of|
|Particle shape:||Spherical||No micropores|
|Specific surface area:||120 m2/g||Retention linearity and loading capacity|
|Median pore diameter:||250 Å||Mass transfer for wide range of analyte shapes and sizes|
|Pore volume:||0.7 m3/g|
|Mean particle diameters:||3 µm, 5 µm||Analytical HPLC columns|
|7 µm||Preparative HPLC columns|
|30 µm||SPE applications|
|Porosity:||75%||Mass transfer within particles|
|% C:||100%||Chemical stability|
|Mechanical strength:||<400="">||Operational particle stability; pressure gradients in packing process|