Which HPLC and UHPLC column compartment is right for you?

Thermo Scientific Vanquish and UltiMate 3000 HPLC and UHPLC column compartments reliably control your separations by ensuring accurate and precise temperature control of the HPLC column. Optional switching valves support advanced configurations, such as automated method scouting, tandem LC and LC-MS, and 2D-LC applications.

Discover HPLC and UHPLC Column Compartments

Column compartment options


Vanquish column compartments



UltiMate 3000 column compartments


Vanquish column compartments provide active eluent pre-heating and advanced column thermostatting. Two thermostatting modes reliably control retention, selectivity and efficiency of your separation, supporting easy method transfer. Optional column switching valves support a large variety of advanced analytical applications. UltiMate 3000 column compartments ensure accurate and precise temperature control for HPLC and UHPLC applications. They can  be used with optional switching valves to enable advanced analytical workflows. We also offer autosamplers with an integrated column compartment as an affordable, space-saving option.

HPLC and UHPLC columns

Need a reliable HPLC column? With over 40 years as a leader in HPLC and UHPLC column technology, you can rely on the quality of Thermo Scientific LC columns. Our extensive family of products offers a variety of particle sizes and column designs to meet all separation needs, including improved resolution, enhanced sensitivity, faster analysis and consistent performance. Whether you are running nano-flow separations, looking for analytes on the analytical scale, or scaling up your separations to semi-prep/preparative flow, our HPLC columns can meet all your chromatographic needs.