Low molecular weight, non-polar organic compounds in food contact materials are typically volatile and have the highest probability to migrate from or through polymeric contact material. Testing of the contact material is typically conducted by headspace sampling followed by gas chromatography and mass spectrometry (GC-MS).

Headspace GC-MS is a popular analytical technique and has been widely used in food packaging studies as it provides analytical advantages of chromatographic resolution, reproducibility, peak capacity and, importantly, extensive spectral libraries to aid in identification. Gas chromatography high resolution mass spectrometry (GC-HRMS) is becoming increasingly popular, enabling the identification and quantification of unknown compounds.

Volatile Analysis for Food Packaging Materials workflow

Volatiles are released from materials using headspace sampling. USP methods suggest the use of valve-and-loop headspace sampling systems. Ultraclean Thermo Scientific™ Chromacol™ headspace vials help ensure low background and leak free seals.

Modular GC allows your choice of injectors, together with helium saver options and the widest range of advanced column technologies, including Thermo Scientific™ TraceGOLD™ GC column phases for volatiles.

Sensitive mass spectrometry delivers both quantitation and qualification of volatiles. Thermo Scientific™ ISQ™ Series Quadrupole GC-MS features a new source design ideal for continuous high-throughput operation.

Simple to operate and fully compliant Thermo Scientific™ Dionex™ Chromeleon™ Chromatography Data System (CDS) software provides mass spectrometry data acquisition and processing for GxP environments.

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Learn more about this reliable and robust HS-GC solution that features a dual detector configuration and is compliant with the EN13628-1:2002 standard method. Suited to routine laboratories, this solution provides integrated MHE data processing for easy and automated quantitative data reporting, eliminating the need for external data manipulation.

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