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Kinases
GPCRs
Ion Channels
Nuclear Receptors
Drug Metabolism
Ubiquitin
Signal Transduction Pathways
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Kinases
Interrogating Multiple Receptor Mediated-MAP Kinase Signailng Pathways in One High Throughput Cell-Based Assay
Tools and Processes to Drive Data Quality and Throughput for Biochemical and Cellular Compound Profiling
Biochemical assays for selectivity profiling across the entire PI3 kinase family
The Adapta™ universal kinase assay: A superior alternative to luciferase-based kinase assays
Comparison of Purified Recombinant AMPK α1β1γ1 and α2β1γ1 Activation and Inhibition using Fluorescence-based Assays
Invitrogens SelectScreen™ Cell-based Pathway and Biochemical Kinase Screening Services
Comparison of Purified Recombinant AMPK
A Homogeneous TR-FRET Assay for Inhibitors of FRAP1 Kinase Activity
Fluorescent High-Throughput Kinase Cascade Assays for Inhibitor Characterization: RAF-MEK-ERK Pathways
A Homogenous Flourescence-Based Assay for mTOR Kinase Activity
LanthaScreen™ TR-FRET Kinase Assays on the Tecan Safire2™ Monochromator-based Plate Reader
Combining Targeted Agents Against Cell-Signaling Components Involved in Cancer: Beta-lactamase’s Robustness and Versatility as a Functional Cell-Based Reporter
FRET-based Ion Channel, GPCR, and Kinase Assay Applications on the Synergy™ HT Multi-Detection Microplate Reader from Bio-Tek
The CellSensor® Pathway System- Using the power of lentivirus and beta-lactamase to study signal transduction pathways
Fluorescent Sensor Proteins for Universal Kinase, Phosphatase, ATPase and GTPase assays
Development of FRET-based ion channel, GPCR and Kinase Assays on the GENios Pro Multifunctional plate reader from Tecan
LanthaScreen™ Reagents for Facile TR-FRET assay development
LanthaScreen™ Assay Development Poster - Screentech 2005
GPCRs
SelectScreen™ Cell-based GPCR Profiling Service: Rapid Profiling of Compounds with Functional Assays in Agonist and Antagonist Mode
Sub-Type Selective Histamine Receptor Cell Lines Utilizing GeneBLAzer® Technology
High Throughput Ready FPRL-1-Ga15-NFAT-bla-CHO-K1 GeneBLAzer Cell Line
Development and Validation of GPCR Cell-Based Assays VPCA1 and VPAC2
A New No-Wash Calcium Assay for HTS
ToxBLAzer™ DualScreen: A Multiplexed beta-lactamase Reporter and Cytotoxicity Readout that Reduces False Hit Rates
FRET-based Ion Channel, GPCR, and Kinase Assay Applications on the Synergy™ HT Multi-Detection Microplate Reader from Bio-Tek
Detecting the FRET response of the GeneBLAzer® Cell Line D1 CRE-bla CHO-K1 to Agonists and Antagonists using the Acumen Explorer 405
GPCRs using ß-lactamase as a reporter system
Comparison of cellular reporter systems: GeneBLAzer and Luciferase
Development of FRET-based ion channel, GPCR and Kinase Assays on the GENios Pro Multifunctional plate reader from Tecan
Combining a Fluo-4 Calcium Mobilization Assay and the Beta-Lactamase Reporter System: Two GPCR Screens with One Cell Line
Ion Channels
FRET-based Ion Channel, GPCR, and Kinase Assay Applications on the Synergy™ HT Multi-Detection Microplate Reader from Bio-Tek
Ion Channel Assay Development and High Throughput Screening Applications Using Voltage Sensor Probes
Development of FRET-based ion channel, GPCR and Kinase Assays on the GENios Pro Multifunctional plate reader from Tecan
Nuclear Receptors
Analysis of PPAR sub-types with selected ligands using biochemical and cell based assays
Tools for the Discovery and Characterization of GR Modulators
Fluorescence-based Biochemical Assays for the Study of Pregnane X Receptor and Constitutive Androstane Receptor
Fluorescence Polarization Assay for Identification of Vitamin D Receptor VDR Ligands
Fluorescence-Based Methods for Characterization of Vitamin D Receptor Ligands
Development of a TR-FRET Coactivator Displacement Assay for ERRα and ERRγ
Concordance of Small Molecule Screening Data Using Cell-Based vs. Biochemical Nuclear Receptor Assays
Analysis of PPAR sub-types with selected ligands using biochemical and cellular assays
Using LanthaScreen technology in the search for tissue selective LXR agonists
A tool box of cell-based and biochemical assays for the study of GR
Drug Metabolism
Fluorescence-based Biochemical Assays for the study of PXR and CAR
Miniaturization and Automation of Cytochrome P450 Inhibition Assays
HTS Assay for CYP2B6 and CYP2E1 Metabolism and Inhibition Using Fluorogenic Vivid® Substrates
Using a β-lactamase Reporter Systems for CYP1A1 Induction in a Cell-Based HTS Assay Format
Cell-Based Assays for the Prediction of CYP1A1 Induction Using the β-lactamase Gene Reporter System and Fluorogenic Vivid® Substrates in HTS Format
A Contemporary Approach to Screen for Cytochrome P450 Metabolism and Inhibition Using Vivid® Fluorogenic Substrates
Characterization of in vitro HTS Assays with Vivid® Fluorogenic Substrates and Recombinant Human CYP1A2, 2D6, 2C9, 2C19, and 3A4
A Screening Strategy for in vivo Prediction of Drug Metabolism Using
in vitro
HTS Assays with Vivid® Fluorogenic Substrates and Recombinant Human CYP3A4
A Novel Approach for in vitro Screening of Recombinant Human CYP2D6 Metabolism and Inhibition
Validation of Fluorogenic Vivid® Probe Substrates for Analysis of CYP450-Drug Interactions
Ubiquitin
Cellular-HTS Assays for the Ubiquitin-Proteasome system in NFκB Signaling
Fluorescent High-Throughput Conjugation and Deconjugation Assays for Ubiquitin-like Proteins SUMO and NEDD8
Fluorescent Assays for Conjugation and Deconjugation of Ubiquitin Proteins
Reagents for High Throughput TR-FRET Assays for Ubiquitination and Deubiquitination
Generic TR-FRET Reagents for Ubiquitination and Deubiquitination Assays
Ubiquitin Related TR-FRET Reagents for HTS
Signal Transduction Pathways
High Through-put Cell-based Assays for Interrogating Wnt-β-catenin Signaling Pathway
Interrogating Multiple Receptor Mediated-MAP Kinase Signailng Pathways in One High Throughput Cell-Based Assay
Flow Cytometry in Cell-Based Assay Development using GeneBLAzer® β-Lactamase Technology
CelLSensor® Cell Lines for Disease-Relevant Pathway Analysis
A High-Throughput Cell-Based Assay for Interrogating Hypoxia-Induced Signaling Pathway
Other
Development of a Time Resolved FRET (TR-FRET) Assay for Beta Secretase
For Research Use Only. Not for use in diagnostic procedures.
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