Obtain terbium, europium and Invitrogen Alexa Fluor 488 or 647 labeled antibodies and let us identify the best antibody pairs for use in our Invitrogen LanthaScreen assay technology with fast and convenient custom antibody labeling and “best pair” analysis services.

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Best antibody pair analysis services

Our Custom Biology team now offers labeling and testing of multiple combinations of antibodies to help you rapidly identify the best donor and acceptor combination for a TR-FRET assay. Potential applications for this analysis include: biomarker detection, phospho protein detection in cell based assays, assay development, and protein-protein interactions.

Advantages of LanthaScreen Assays and TR-FRET

LanthaScreen assays are a popular fluorescent assay choice for drug discovery labs. The technology utilizes Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET); and TR-FRET assays are less susceptible to compound interference than other assay formats and may be applied to multiple target classes.

When terbium or europium-labeled molecules are brought into proximity with Alexa Fluor 488 or Alexa Fluor 647 labeled, energy transfer takes place causing an increase in acceptor fluorescence and a decrease in donor fluorescence. These fluorescent signals can be read in a time-resolved manner to reduce assay interference and increase data quality.

Our service: A simple process

  1. Send us an inquiry online to discuss your requirements
  2. Send us your antibody—up to 100 μg for ACCESS program; 1 mg or more for Standard service.
  3. Our Custom Biology R&D team will label the antibody with either Terbium or Europium and qualify the labeling characteristics
  4. Material is shipped back to you typically within 1–2 weeks

TR-FRET antibody labeling: Service options

Choose the service that best fits your antibody labeling requirements:

ServiceAntibody quantityAverage turn-around timeCost
StandardMore than 100 μg1–2 weeks$$
ACCESS Program20–100 μg1–2 weeks$
"Best Antibody Pair" Screening Program20 μg, multiple combinations of antibodiesvaries by project$$

For more information on our custom antibody labeling services, send us an online inquiry. A Thermo Fisher Scientific representative will respond to your inquiry typically within 1–2 business days.

For Research Use Only. Not for use in diagnostic procedures.

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