Identifying metabolites in challenging matrices shouldn’t be a challenge in itself. Chromatographically separating metabolites from one another and obtaining accurate identification each time, every time, is simple to achieve with the right tools. Even when something unexpected appears, you can be sure that it won’t be a challenge to elucidate and identify with confidence; no one likes a surprise that cannot be explained.
Typical LC-MSn workflows have to compromise among spectral quality, specificity and coverage. Capture high-quality MSn spectral data on every compound in your sample automatically with the AcquireX intelligent data acquisition workflow. There is no need to manually interrogate your data to identify background ions for exclusion, or to create inclusion lists. Interrogation can be automated, from background exclusion to the inclusion of sample compounds.
Save time for your metabolite identification studies with Thermo Scientific™ Compound Discoverer™ software. Compound Discoverer software ensures confident compound identification and structural elucidation for pharmaceutical metabolism studies as well as aiding impurity analysis. The software helps researchers plan how data will be collected, organized, stored and reported with the final result in mind. Its node-assembled processing workflows, advanced algorithms, and study-oriented data storage allow users to quickly process and assemble data collected from multiple samples into a unified report.
Screen, identify and quantify compounds in complex samples rapidly and with confidence using the Thermo Scientific™ Orbitrap Exploris 240 Mass Spectrometer.. This compact LC-MS system delivers high confidence results with unmatched spectral clarity. Assign more spectral features with the application flexibility, speed, dependability, and operational simplicity required by laboratories performing clinical research and DMPK applications.
Designed with innovative technology and fine detail, the Thermo Scientific™ Vanquish™ UHPLC System delivers a new standard in high-end UHPLC—more results with better separations and easier interaction simultaneously, without compromise. This fully integrated and biocompatible system features high sample capacity for high-throughput workflows, industry-leading pumping performance, amazingly high S/N and linearity, two-mode thermostatting, active preheating, and more in a system that's driven by class leading informatics.