MEM Minimum Essential Medium

Gibco Minimum Essential Media (MEM) is patterned after Eagle’s Media and is well suited for the growth of a broad spectrum of mammalian cells.

One of the most commonly used of all cell culture media, MEM can be used with a variety of suspension and adherent mammalian cells, including HeLa, BHK-21, 293, HEP-2, HT-1080, MCF-7, fibroblasts, and primary rat astrocytes.

We offer a variety of MEM modifications for a range of cell culture applications.

NEW Gibco Human Plasma-like Medium

Gibco Human Plasma-like Medium (HPLM) is a new formulation designed to resemble the natural cellular environment found in the body, mimicking the metabolic profile of human plasma.

  • Physiologically relevant - designed to resemble the natural cellular environment found in the body formulated with more than 60 polar metabolites and salt concentrations
  • Peer reviewed – extensive research publications completed using HPLM formulation

Discover Human Plasma-like Medium

Choose the right MEM

Select the right Gibco MEM for your cell culture. Browse the catalog and you’ll be able to narrow the list according to:

  • Glutamine / GlutaMAX supplementation
  • Phenol red indicator
  • Liquid vs powder formats
  • Serum supplementation
  • Sodium pyruvate additive
  • Application

Specialty MEM formulations

Take your cell culture to the next level with enhanced formulations of your everyday favorites.

  • Allows for a reduction of FBS supplementation by at least 50% with no change in growth rate or morphology
  • Ideal for use during cationic lipid transfections

Choose Opti-MEM

Need a custom MEM formulation? Customize your MEM online

cell culture media icon GMP manufacturing

Gibco cell culture products are manufactured in facilities that are compliant with current good manufacturing practices (GMP) for medical devices and adheres to a robust quality management system.

Learn more about GMP manufacturing

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We are committed to delivering products that serve the research needs of our customers, while striving to develop them in a way that minimizes our use of natural resources and our impact on the environment.

Learn more about sustainable solutions


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