siRNA Transfection

Gene silencing or knockdown can be done easily now in most cell types, but there are a few things you need to consider before starting:

  • First, you’ll need to design the siRNA (small interferring RNA) against your gene
  • Second, you’ll need to deliver it to the cells effectively with a siRNA transfection procedure

Which siRNA transfection product is right for you?

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 High efficiency versatile reagent for a wide range of common cell typesMost efficient versatile reagent for the widest range of cell types including difficult-to-transfect cellsMost efficient reagent for siRNA/miRNA delivery. Efficient gene knock-down.High-efficiency electroporation for all cell lines. Best for Primary & Stem Cells
 Lipofectamine 2000
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Lipofectamine 3000
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Lipofectamine RNAiMAX
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Neon Transfection System
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Top Selling FormatCatalog #11668-019 - 1.5 mLCatalog #L3000-015 - 1.5 mLCatalog #13778-075 - 0.75 mLCatalog #MPK5000S
Sample Type
  • DNA
  • RNA
  • Co-transfection
  • DNA
  • RNA
  • Co-transfection
  • RNA
  • DNA
  • RNA
  • Co-transfection
  • Protein
Transfection EfficiencyHighSuperiorSuperiorMaximal
Cell ViabilityHighSuperiorSuperiorGood
ProtocolDownload ProtocolDownload Protocol Download ProtocolDownload Protocol

Support

Transfection support center
Find technical support recommendations for your lipid-based transfection workflows and for electroporation methods, including tips for experimental setup and in-depth troubleshooting help.