GeneTitan Instrument

Transform your lab with a GeneTitan™ instrument and experience the superior power of streamlining array processing for discovery, exploration, and screening. Both the GeneTitan Instrument for expression applications and the GeneTitan™ Multi-Channel (MC) Instrument for expression and genotyping seamlessly integrate hybridization, washing, and imaging in a single instrument to provide automated array processing—whether you are performing basic or applied research.

  • Scalable—meets both medium- and high-throughput needs, enables fast time to data with fewer resources.
  • Efficient—condenses hands-on processing time to as little as 30 minutes, images an array in less than five minutes, and operates unattended overnight.
  • Flexible—supports gene expression and genotyping studies on multi-format array plates.
  • Accurate—designed to deliver high-quality, consistent data by processing multiple samples under identical conditions.
  • Adaptable—creates flexible workflows and sample registration via the GeneChip™ Command Console™ Software (AGCC)

The flexibility you want—multiple formats and customized solutionsfor gene expression and genotyping studies

GeneTitan™ instruments together with Affymetrix™ High-Throughput (HT) Array Plates provide the first automated solution for microarray processing. With a broad selection of array plate formats, you can easily transition from discoveries through genome-wide SNP genotyping, to comprehensive explorations of gene expression profiles relating to important biological phenotypes, such as disease or drug response. 

Genotyping Studies

GeneTitan Instruments together with Affymetrix Array Plates enable a wide menu of applications in gene expression and genotyping studies

Automated array processing

A GeneTitan™ Instrument takes your experiments from prepared samples to primary analysis without user intervention. And unlike any other system currently on the market, the instrument automates all array processing and plate transfers for a fully automated workflow

Automated GeneTitan instruments enable

  • Lower labor and array costs
  • Highest data consistency
  • More time with biology—not the technology

Enables high-quality, consistent data every time by processing multiple samples under identical conditions

The instrument condenses eight hours of hands-on time into as little as 30 minutes for any microarray platform, and multiplexes samples with minimal operator intervention, reducing labor needs and freeing up skilled lab personnel for other priorities. 

Highest productivity
The instrument operates unattended overnight, providing up to 10 times the productivity of other platforms. And, the unique degree of automation means superior reproducibility and increased confidence in your results.

Set up—Load—Go

Set up – Load – Go

A single operation for hands-free, unattended array processing. The user simply loads the arrays, prepared samples, and reagents into the instrument 

Primary analysis can be completed automatically to rapidly assess the quality of each experimental study

Genotyping solutions

Superior accuracy, productivity, and customization, with a single assay

The Axiom™ Genotyping Solution includes the GeneTitan™ MC Instrument and offers a fully automated workflow for a broad selection of applications including genome-wide association studies (GWAS), replication studies, candidate-gene association, and targeted genotyping for human disease research and agricultural genomics. 

Genotyping on the GeneTitan MC Instrument enables

  • Fastest time to data 
  • A single scientist to process thousands of samples
  • High control over genotyping production 

Reduce complexity

The GeneTitan MC Instrument is the only platform that lets you generate robust and reliable genotypes with minimal user intervention while helping reduce costs and processing complexity. The Axiom Genotyping Solution includes Affymetrix-supported manual or automated target prep methods and automation-friendly reagent kits for preparing samples to process in the instrument. 

Scalable and customized solutions

Choose from a suite of pre-designed population-specific Axiom™ Genome-Wide Array Plates for genetic mapping. Or, design your own custom Axiom™ myDesign™ Array Plate with 1,500 to 2.6 million SNPs by choosing from our database of 11 million validated genomic markers and your own proprietary target markers from sequencing initiatives.


The GeneTitan MC Instrument enables one bench scientistto manage a throughput of more than 760 samples per week with less than 2.5 hours of hands-on time per 96 samples.

Flexible workflow

Integrate Microsoft® Windows GUI-based Genotyping Console™ Software (GTC) or automation-friendly command line-based Affymetrix Power Tools (APT) for completing the primary genotyping analysis. The flexible software workflow with simplified data management allows you to easily share your results and seamlessly integrate with third-party software packages.

The GeneTitan MC instrument generates robust and reliable genotypes that can be visualized using the SNP Cluster graph through a user-friendly graphical interface

Gene expression

Discovery, validation, and screening, with a single instrument

With either the GeneTitan Instrument or the GeneTitan MC Instrument you will be able to streamline array processing for whole-transcriptome or 3’ IVT gene expression analysis in human and model and applied research organisms. Regardless of your throughput requirements, you can rapidly identify and validate gene expression profiles and discover biologically relevant pathways.

Gene expression on both GeneTitan Instruments offers

  • Consistently reproducible data
  • High accuracy in expression analysis
  • More confidence in your results 

Latest content

Choose from the most popular and widely cited microarrays for whole-transcriptome or classical 3’ based designs in a convenient medium- to high-throughput format for low-cost expression profil-ing of human, mouse, and rat. You may also customize your array content for any available annotated genome, focus region, or control sequence using our MyGeneChip™ Custom Program. 

Ease of use

Automation-friendly reagent kits easily integrate with upfront Affymetrix-supported automated target prep methods. Alternately, reagent kits designed for the manual assay give you the flexibility of preparing samples for lower throughput.

GeneTitan Instruments generate highly reproducible and concordant data and can detect changes in gene expression at or above the 1.5 pM concentration.

Automatic answers

Use Expression Console™ Software or any of the GeneChip-compatible™ Partner Solutions for probe set summarization and gene-level analysis. Follow up with NetAffx™ analysis to correlate array results with array design and annotation information. Alternately, you may build automated primary analysis pipelines for a completely automated workflow, using Affymetrix Power Tools Software and the data transfer tools provided with the instrument control software.

Results of the analysis of 3’ IVT expression data demonstrate the ability to achieve consistently reproducible data 

Streamlined software

And easy-to-interpret results

GeneTitan™ instruments come installed with the popular, file-based Command Console™ Software for instrument control. The primary analysis can be completed using the Expression Console™ Software for gene expression profiling or the Axiom Analysis Suite Software for genotyping analysis.

Genotyping and expression solutions

Available on GeneTitan instruments

ApplicationsProductsAnalysis software
GWAS and replication*
  • Axiom™ Genome-Wide Arrays
  • myDesign™ Custom Arrays
  • Axiom Analysis Suite
  • Affymetrix Power Tools
Fine mapping and candidate genes*
  • Axiom™ myDesign™ Targeted Genotyping Arrays
Haplotype structure*
  • Axiom™ Genomic Screening Service
Agricultural genomics*
  • Axiom™ Genome-Wide Bovine Array
  • myDesign™ Custom Arrays
3’ IVT expression
  • PrimeView™ Human Gene Expression Array
  • Expression Console™ Software
  • Affymetrix Power Tools
  • GeneChip-compatible™ Software
  • HT HG-U133+ PM Array Plate
  • HT Human Genome U133 Array Plate Set
  • HT MG-430 PM Array Plate
  • HT Mouse Genome 430 Array Plate Set
  • HT RG-230 PM Array Plate
  • HT Rat Focus Array Plate
  • Model and applied research organism array plates (ordered through the MyGeneChip™ Custom Arrays Program)
  • MyGeneChip™ Custom Arrays
Whole-transcriptome expression
  • Human Gene 1.1 ST Array Plate
  • Mouse Gene 1.1 ST Array Plate
  • Rat Gene 1.1 ST Array Plate
  • Model and applied research organism array plates
  • MyGeneChip™ Custom Arrays