Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
In the market today, C18 is still the go-to chemistry for most applications, and there are lots of Reversed-phase, column choices, but when separating both charged and neutral analytes C18 alone won’t be enough to achieve the needed resolution. This is where the unique surface chemistries of mixed-mode columns will help.
Having the right column for your application is critical to obtaining the analytical results and throughput you need. This presentation will help simplify how to choose the correct phase, particle size, and column dimensions, as well as explain how these choices impact your analytical and workflow needs. We will highlight how varying phases might affect your analysis.
Ghost peaks can be scary, shifting peaks can be troubling, and broad peaks can be painful. Let’s talk about some common problems chromatographers face and steps to troubleshoot what’s REALLY going on with your analysis. Join us for the first part of chromatography troubleshooting and learn how to sharpen your skills and your peak shape!
Learn how to modernize any classic HPLC method. Transferring a method to ultra-high performance can be easy and will enable you to take advantage of the latest advances in columns and instrument technologies. This educational webinar will emphasize the benefits of UHPLC to routine quality testing and provide you with takeaway tips on how to effectively understand method transfer in your lab.
We’ve learned a lot about troubleshooting EASY-Spray columns and wanted to share some tips with you. Join us to learn how you can optimize your EASY-Spray workflow and signs to watch for that might indicate a problem.
Buffers are incredible if they are made and used properly. If not, they could suppress your analytes and your mood. Improper preparation and storage of buffers can negatively affect the detection and quantitation of any ionic species. This presentation will discuss how to optimize your buffers and as a result, your chromatography.
Column care can directly impact the quality of your chromatography. Learn how to properly care for your columns and how to troubleshoot if things “go astray.” Join us for HPLC column troubleshooting part 2. Your columns will thank you!
Polar analytes are complex. We’ve got a full set of columns that will help you optimize your method for polar substances. Let us teach you about Hypercarb columns, which revolutionized chromatography of polar analytes, and let’s also talk about column chemistries that could “charge” your workflow.
Join scientific experts from NIBRT in Dublin, Ireland and Thermo Fisher Scientific for the latest analytical advances for intact protein characterization.
Biopharmaceutical manufacturers need to closely monitor the charge variant profiles of their monoclonal antibodies (mAbs). It is critical that the method selected provide high resolution data and consistent column to column performance. In this webinar, learn about the newest addition in our comprehensive portfolio of products for bio separations.
In this webcast, learn about the wide variety of phases, hardware, and method development tools available to help you chose the most appropriate preparative HPLC column. Choosing the right preparative LC column packed with the right stationary phases and in the right hardware will help you maximize your performance.
In this on-demand webinar, learn about the best chemistries for sample types, and understand the benefits unique selectivity offers to improve resolution in your sample matrices, and decode different phase options available, facilitating efficient method development and eliminating the guess work.
Monoclonal antibodies and other similar biotherapeutics are extremely hard to characterize, due to an almost infinite number of variants, exacerbated by post translational modifications such as charge variance and aggregation. The number, type and location of glycans adds a further degree of complexity.
We discuss these difficulties and also the current technologies used to maximize glycan separation capabilities and structural elucidation.
Learn how to achieve superior reversed phase oligonucleotide separations using the unique chemistry designed for analysis of oligonucleotides and double-stranded (ds) DNA/RNA fragments using LC-UV or LC-MS.
Learn how to utilize superior resolving power to achieve in depth characterization of therapeutic antibodies at protein, subunit and peptide levels using the novel capillary Thermo Scientific MabPac RP column in either stand-alone or integrated EASY-Spray design coupled to an LC-MS system.
In this webinar, you will learn about key considerations when switching from a glass container to plastic. What to do when volumes and dimensions of the cavities are different — are sample volume and needle adjustment necessary? How to ensure reproducibility by sealing the plate cavities effectively using low boiling solvents.
Looking to maximize your chromatography and mass spectrometry systems, to ensure quality ultra-trace analysis? In this webinar, discover how the addition of inert-glass autosampler vials can optimize chromatography and mass spectrometry systems. Inert-glass vials ensure that the sample does not stick to the glass wall of the vial and reduces the chances of contaminant, increasing productivity and maintaining quality.
This presentation Introduces a new automated, efficient and highly reproducible approach to peptide mapping and associated compliant LC and LC-MS software.
Current sample preparation techniques utilized for peptide mapping are complex, and prone to error, this can have a dramatic effect on reanalysis rates, transfer and implementation of methods at different sites. This webcast details how new technologies can deliver peptide mapping which is: Fast, Easy for untrained operators, Reproducible and transferable - and provides high quality results with low Post Translational Modifications (PTMs)
In this webinar series, four new technologies will be demonstrated that dramatically improve upon established mapping workflows and help increase confidence in biopharma peptide mapping.
Webinar 1 - How to get full coverage peptide maps using high resolution accurate mass spectrometry.
In this webinar series, four new technologies will be demonstrated that dramatically improve upon established mapping workflows and help increase confidence in biopharma peptide mapping.
Webinar 2 - Take the Smart Route to Protein Digestion. How to increase reproducibility whilst reducing preparation time.
In this webinar series, four new technologies will be demonstrated that dramatically improve upon established mapping workflows and help increase confidence in biopharma peptide mapping.
Webinar 4 - Peptide Separations with Pinpoint Precision. How to achieve ultimate retention time reproducibility and high resolution separation of peptides.