Confident Quantitation with Triple Quadrupole LCMS

LC/MS platform solutions designed to help you address your goals

From addressing complexities of molecules and matrices, to ensuring ease-of-use while satisfying regulatory requirements—today’s challenges in targeted quantitation involve more than just measuring concentrations of target analytes. Achieve ultimate confidence in your data quality with a robust, sensitive, reproducible, and reliable targeted quantitation method using our new liquid chromatography mass spectrometry (LC/MS) workflow solutions.

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40 year anniversary of Thermo Scientific development and success of triple quadrupole mass spectrometers

For today and what's next

TSQ Altis Quadrupole Mass Spectrometer

Ultimate sensitivity & selectivity to meet tomorrow’s standards today

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For everyday excellence

TSQ Quantis Quadrupole
Mass Spectrometer

Everyday quantitation workhorse to meet today’s standards

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For a new level of confidence

TSQ Fortis Triple Quadrupole Mass Spectrometer

Quality data across workflows for users at all levels of expertise

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Product comparison

Triple Quad Product ComparisonAccess MaxFortisEnduraQuantis
Altis
Sensitivity+++++++++++++++++
Resolution+++++++++++
Scan Speed++++++++++++++++++
Applications across multiple matrices
Targeted quantitation in ProteomicsNoNoYesYesYes
Peptide and protein quantitation (Biopharma)NoNoYesYesYes
Small molecule quantitation (Pharma, Clinical Research)YesYesYesYesYes
Small molecule mixture quantitation (Environmental Safety, Food Safety, Forensic Toxicology, Pharma)YesYesYesYesYes
Analysis and targeted quantitation of trace impurities (Impurity Quantitation)YesYesYesYesYes
Targeted quantitation in Omics (metabolomics, lipidomics)NoYesYesYesYes
Critical Features
MRM for reliable identificationYesYesYesYesYes
Multiple Source CompatibilityYesYesYesYesYes
High Resolution SRM: for increased selectivity and sensitivity for analytes or multiple analytes in complex matrices+++++++++++
Segmented quadrupoles for increased ion efficiencyNoYesNoYesYes
Neutral blocker for increased robustnessYesYesYesYesYes
Increased dynodes in detector for increased lifetime and better linear dynamic rangeNoYesNoYesYes
APCI compatible with HESI sourceNoYesNoYesYes
Polarity Switching: Fast switching with stabilization enable faster quantitation assays for every molecule type+++++
System Remote MonitoringYesYesYesYesYes
Assist with 21 CFR Part 11 Compliance (appropriate software)NoYes. With LCQUAN™ SoftwareYes. With LCQUAN™ SoftwareYes. With LCQUAN™ SoftwareYes. With LCQUAN™ Software
Instrument IQ/OQ assistNoYesYesYesYes
Thermo Fisher Cloud: Access, process, review data whenever you like, from wherever you areNoNoYesYesYes
Wi-Fi Connectivity: Access your data, Check your assay performance remotelyYesYesYesYesYes
Size27x30x33 (in)27x30x33 (in)27x30x33 (in)27x30x33 (in)27x30x33 (in)
IVD PlatformNoNoAvailable in certain countriesNoNo
Compatible separation technologiesUltiMate, Vanquish, Multiplexing, Capillary LC, Other vendorsUltiMate, Vanquish, Multiplexing, Capillary LC, Other vendorsUltiMate, Vanquish, Other vendors, IC, Multiplexing, Capillary LC, NanoLCUltiMate, Vanquish, Other vendors, IC, Multiplexing, Capillary LC, NanoLCUltiMate, Vanquish, Other vendors, IC, Multiplexing, Capillary LC, NanoLC
Compatible Software?Xcalibur, TraceFinderXcalibur, TraceFinder, ChromeleonXcalibur, TraceFinder, ChromeleonXcalibur, TraceFinder, ChromeleonXcalibur, TraceFinder, Chromeleon
Library availabiltyYesYesYesYesYes

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