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Upstream Bioprocessing
Educational Resources
Upstream bioprocessing has made great productivity gains over the last decade. Modern cell culture systems are now producing notably higher titers while also decreasing the time from bench to production bioreactor. Please find below all of the latest resources on upstream processing.
Advancing Microbial Bioproduction
Learn how to benefit from recent technology advances to successfully develop your bioprocess.
Cell-based biomanufacturing process
Hear about the latest advances in serum-free, chemically defined media.
Early process development options and speed to clinic
Learn how some key early technology choices can positively impact your bioprocess development agility and time to clinic.
Monoclonal Antibody
This webinar demonstrates the critical role of media and supplements in influencing protein quality attributes.
Next level innovation in Single-use bioreactors
Listen to this on-demand webinar to hear about the design aspects of the Hyperforma S.U.B.
Peptone Media
This webinar demonstrates the benefits of peptones and how they can be used to enhance process performance and consistently yield a high-quality product.
Quality and compliance in single-use systems
Discover valuable risk mitigation strategies addressing important issues such as integrity or particulates.
Robust continuous upstream processing
Discover the latest advances in the field of perfusion media performance.
Global Regulators' FAQs on CMC in IND/BLA Filing
Hear from our experts: A retrospective look at past Mycoplasma validation queries and responses
Validation Guidance for Residual Host Cell DNA Testing
Watch this webinar and learn more about validation of a qPCR assay for residual host cell DNA quantitation.
HyPerforma Single-Use Fermentor
Watch this video and learn about the unique features and advantages of our first single-use system specifically engineered for microbial fermentation.
Thermo Scientific Bioprocess Equipment and Automation Solutions from R&D to Production
Research and development, process development, and pilot plants involved in scale-up and technology transfer can face significant setbacks such as time and data loss due to a lack of efficient, traceable data transfer.
Enabling cell & gene therapy raw materials standardisation
The quality of raw materials needs to be considered according to the stage of development of the cell or gene therapy.
End-user evaluation of 30 L and 300 L HyPerforma S.U.F.s and scale-down model
In moving processes from bench to pilot and ultimately production fermentors, it is critical to have a reliable scaledown model.
ExpiCHO system
As competition and growth in the biotherapeutic industry continues, the need to reduce cell line development costs and decrease time-to-market is more crucial.
Nunc Cell Factory equipment
Scaling up adherent cell culture can be a difficult process for many vaccine, cell therapy, gene therapy, and viral vector manufacturers
Production of therapeutic plasmid DNA in single-use fermentors
The manufacturing of plasmid DNA is becoming a supply bottleneck due to rapidly growing demand for various gene-targeting biotherapeutics
Quantifying residual DNA using qPCR
Find out more about the development of a novel residual DNA assay for HEK-293.
Single-Use Bioreactor enhancements for high-density fed-batch cultures
Improvements in single-use systems have allowed implementation of high-demand cultures in emerging bioprocess workflows.
Single-use bioreactor performance for scalable cell culture
Adherent cell cultures, such as those with Vero cells, are often more challenging than their suspension-based counterparts.
S.U.B. enhancements for high-density perfusion cultures
Improvements in single-use systems have allowed implementation of high-density cultures in emerging bioprocess workflows.
Bioprocessing resources
Access a targeted collection of scientific application notes, case studies, posters, white papers and more for bioprocessing:
Style Sheet for Global Design System